Escape From Treatment; the Different Faces of Leukemic Stem Cells and Therapy Resistance in Acute Myeloid Leukemia

by Noortje van Gils, Fedor Denkers, Linda Smit
Published 2021-05-01

Specific Depletion of Leukemic Stem Cells: Can MicroRNAs Make the Difference?

by Tania Martiáñez Canales, David C. de Leeuw, Eline Vermue, Gert J. Ossenkoppele, Linda Smit
Published 2017-06-01

The Novel Oral BET-CBP/p300 Dual Inhibitor NEO2734 Is Highly Effective in Eradicating Acute Myeloid Leukemia Blasts and Stem/Progenitor Cells

by Noortje van Gils, Tania Martiañez Canales, Eline Vermue, Arjo Rutten, Fedor Denkers, Tiem van der Deure, Gert J. Ossenkoppele, Francis Giles, Linda Smit
Published 2021-08-01

Normal hematopoietic stem cells within the AML bone marrow have a distinct and higher ALDH activity level than co-existing leukemic stem cells.

by Gerrit J Schuurhuis, Michael H Meel, Floris Wouters, Lisa A Min, Monique Terwijn, Nick A de Jonge, Angele Kelder, Alexander N Snel, Sonja Zweegman, Gert J Ossenkoppele, Linda Smit
Published 2013-01-01

IGFBP7 Induces Differentiation and Loss of Survival of Human Acute Myeloid Leukemia Stem Cells without Affecting Normal Hematopoiesis

by Han J.M.P. Verhagen, Noortje van Gils, Tania Martiañez, Anna van Rhenen, Arjo Rutten, Fedor Denkers, David C. de Leeuw, Marjon A. Smit, Mei-Ling Tsui, Louise L.E. de Vos Klootwijk, Renee X. Menezes, Meyram Çil, Margaretha G.M. Roemer, Eline Vermue, Stan Heukelom, Sonja Zweegman, Jeroen J.W.M. Janssen, Gert J. Ossenkoppele, Gerrit Jan Schuurhuis, Linda Smit
Published 2018-12-01