Effects of antiepileptic drugs in a new TSC/mTOR‐dependent epilepsy mouse model

by Linda M. C. Koene, Saskia E. vanGrondelle, Martina Proietti Onori, Ilse Wallaard, Nathalie H. R. M. Kooijman, Annabel vanOort, Jadwiga Schreiber, Ype Elgersma
Published 2019-07-01

RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity.

by Martina Proietti Onori, Linda M C Koene, Carmen B Schäfer, Mark Nellist, Marcel de Brito van Velze, Zhenyu Gao, Ype Elgersma, Geeske M van Woerden
Published 2021-05-01