Differentiation and Function of Follicular CD8 T Cells During Human Immunodeficiency Virus Infection

by Minglu Xiao, Xiangyu Chen, Ran He, Lilin Ye
Published 2018-05-01

Molecular Basis of the Differentiation and Function of Virus Specific Follicular Helper CD4+ T Cells

by Qizhao Huang, Qizhao Huang, Jianjun Hu, Jianfang Tang, Lifan Xu, Lilin Ye
Published 2019-02-01

ZIKV infection induces robust Th1-like Tfh cell and long-term protective antibody responses in immunocompetent mice

by Huabin Liang, Jinyi Tang, Zhihua Liu, Yuanhua Liu, Yuanyuan Huang, Yongfen Xu, Pei Hao, Zhinan Yin, Jin Zhong, Lilin Ye, Xia Jin, Haikun Wang
Published 2019-08-01

Antigen-specific CD8+ T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin

by Yikun Yao, Siyuan Chen, Mengtao Cao, Xing Fan, Tao Yang, Yin Huang, Xinyang Song, Yongqin Li, Lilin Ye, Nan Shen, Yufang Shi, Xiaoxia Li, Feng Wang, Youcun Qian
Published 2017-05-01

CD160 Plays a Protective Role During Chronic Infection by Enhancing Both Functionalities and Proliferative Capacity of CD8+ T Cells

by Linxia Zhang, Anli Zhang, Anli Zhang, Jun Xu, Chao Qiu, Lingyan Zhu, Chenli Qiu, Weihui Fu, Ying Wang, Lilin Ye, Yang-xin Fu, Chen Zhao, Xiaoyan Zhang, Jianqing Xu
Published 2020-09-01

The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection

by Pengcheng Wang, Pengcheng Wang, Youping Wang, Luoyingzi Xie, Minglu Xiao, Jialin Wu, Lifan Xu, Qiang Bai, Yaxing Hao, Qizhao Huang, Xiangyu Chen, Ran He, Baohua Li, Sen Yang, Yaokai Chen, Yuzhang Wu, Lilin Ye
Published 2019-03-01

The Kinase Complex mTOR Complex 2 Promotes the Follicular Migration and Functional Maturation of Differentiated Follicular Helper CD4+ T Cells During Viral Infection

by Yaxing Hao, Yifei Wang, Xiaobing Liu, Xia Yang, Pengcheng Wang, Qin Tian, Qiang Bai, Xiangyu Chen, Zhirong Li, Jialin Wu, Zhunyi Xie, Xinyuan Zhou, Yuyang Zhou, Zhinan Yin, Zhinan Yin, Yuzhang Wu, Lilin Ye
Published 2018-05-01

The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity

by Leiqiong Gao, Jing Zhou, Sen Yang, Lisha Wang, Xiangyu Chen, Yang Yang, Ren Li, Zhiwei Pan, Jing Zhao, Zhirong Li, Qizhao Huang, Jianfang Tang, Li Hu, Pinghuang Liu, Guozhong Zhang, Yaokai Chen, Lilin Ye
Published 2021-03-01

METTL3-dependent m6A modification programs T follicular helper cell differentiation

by Yingpeng Yao, Ying Yang, Wenhui Guo, Lifan Xu, Menghao You, Yi-Chang Zhang, Zhen Sun, Xiao Cui, Guotao Yu, Zhihong Qi, Jingjing Liu, Fang Wang, Juanjuan Liu, Tianyan Zhao, Lilin Ye, Yun-Gui Yang, Shuyang Yu
Published 2021-02-01

The Transcription Factor TCF1 Preserves the Effector Function of Exhausted CD8 T Cells During Chronic Viral Infection

by Yifei Wang, Jianjun Hu, Yiding Li, Minglu Xiao, Haoqiang Wang, Qin Tian, Zhirong Li, Jianfang Tang, Li Hu, Yan Tan, Xinyuan Zhou, Ran He, Yuzhang Wu, Lilin Ye, Zhinan Yin, Zhinan Yin, Qizhao Huang, Lifan Xu
Published 2019-02-01

Bcl6 Preserves the Suppressive Function of Regulatory T Cells During Tumorigenesis

by Yiding Li, Zhiming Wang, Huayu Lin, Lisha Wang, Xiangyu Chen, Qiao Liu, Qianfei Zuo, Jianjun Hu, Haoqiang Wang, Junyi Guo, Luoyingzi Xie, Jianfang Tang, Zhirong Li, Li Hu, Litian Xu, Xinyuan Zhou, Lilin Ye, Qizhao Huang, Lifan Xu
Published 2020-05-01

The lncRNA Snhg1-Vps13D vesicle trafficking system promotes memory CD8 T cell establishment via regulating the dual effects of IL-7 signaling

by Yanyan Zhang, Baohua Li, Qiang Bai, Pengcheng Wang, Gang Wei, Zhirong Li, Li Hu, Qin Tian, Jing Zhou, Qizhao Huang, Zhiming Wang, Shuai Yue, Jialin Wu, Liuqing Yang, Xinyuan Zhou, Lubin Jiang, Ting Ni, Lilin Ye, Yuzhang Wu
Published 2021-03-01

Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function

by Fangjie Wang, Meng Meng, Banghui Mo, Yao Yang, Yan Ji, Pei Huang, Wenjing Lai, Xiaodong Pan, Tingting You, Hongqin Luo, Xiao Guan, Yafei Deng, Shunzong Yuan, Jianhong Chu, Michael Namaka, Tiffany Hughes, Lilin Ye, Jianhua Yu, Xiaohui Li, Youcai Deng
Published 2018-11-01

Dichotomous Roles of Programmed Cell Death 1 on HIV-Specific CXCR5+ and CXCR5− CD8+ T Cells during Chronic HIV Infection

by Yan-Mei Jiao, Hong-Ge Yang, Hui-Huang Huang, Bo Tu, Shao-Jun Xing, Lin Mao, Wei Xia, Ran He, Ji-Yuan Zhang, Ruo-Nan Xu, Lei Jin, Ming Shi, Zhe Xu, En-Qiang Qin, Xi-Cheng Wang, Hao Wu, Lilin Ye, Fu-Sheng Wang
Published 2017-12-01

Sensitivity of SARS-CoV-2 Variants to Neutralization by Convalescent Sera and a VH3-30 Monoclonal Antibody

by Shuai Yue, Zhirong Li, Yao Lin, Yang Yang, Yang Yang, Mengqi Yuan, Zhiwei Pan, Li Hu, Leiqiong Gao, Jing Zhou, Jianfang Tang, Yifei Wang, Qin Tian, Yaxing Hao, Juan Wang, Qizhao Huang, Lifan Xu, Bo Zhu, Pinghuang Liu, Kai Deng, Kai Deng, Li Wang, Lilin Ye, Xiangyu Chen, Xiangyu Chen
Published 2021-09-01

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses

by Jun Deng, Qian Chen, Zhian Chen, Kaili Liang, Xin Gao, Xiaohui Wang, Fadzai V. Makota, Hong Sheng Ong, Yanmin Wan, Kaiming Luo, Dongcheng Gong, Xiang Yu, Sarina Camuglia, Qunxiong Zeng, Tao Zhou, Feng Xue, Jing He, Yunbo Wei, Fan Xiao, Jianyang Ma, Danika L. Hill, Wim Pierson, Thi H. O. Nguyen, Haibo Zhou, Yan Wang, Wei Shen, Lingyun Sun, Zhanguo Li, Qiang Xia, Kun Qian, Lilin Ye, Steven Rockman, Michelle A. Linterman, Katherine Kedzierska, Nan Shen, Liwei Lu, Di Yu
Published 2021-05-01