ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.

by Bianca M Sirbu, Sarah J Lachmayer, Verena Wülfing, Lara M Marten, Katie E Clarkson, Linda W Lee, Liliana Gheorghiu, Lee Zou, Simon N Powell, Jochen Dahm-Daphi, Henning Willers
Published 2011-01-01

Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity

by Lynnette Marcar, Kankana Bardhan, Liliana Gheorghiu, Patrick Dinkelborg, Heike Pfäffle, Qi Liu, Meng Wang, Zofia Piotrowska, Lecia V. Sequist, Kerstin Borgmann, Jeffrey E. Settleman, Jeffrey A. Engelman, Aaron N. Hata, Henning Willers
Published 2019-06-01