Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: analysis of structural data for future drug design

by Lidia Ciccone, Nicoló Tonali, Susanna Nencetti, Elisabetta Orlandini
Published 2020-01-01

Neuroglobin and neuroprotection: the role of natural and synthetic compounds in neuroglobin pharmacological induction

by Lidia Ciccone, Susanna Nencetti, Simone Socci, Elisabetta Orlandini
Published 2021-01-01

Natural Marine and Terrestrial Compounds as Modulators of Matrix Metalloproteinases-2 (MMP-2) and MMP-9 in Alzheimer’s Disease

by Lidia Ciccone, Jennifer Vandooren, Susanna Nencetti, Elisabetta Orlandini
Published 2021-01-01

Application of PROTAC strategy to TTR-Aβ protein-protein interaction for the development of Alzheimer’s disease drugs

by Nicoló Tonali, Susanna Nencetti, Elisabetta Orlandini, Lidia Ciccone
Published 2021-01-01

Physiological Metals Can Induce Conformational Changes in Transthyretin Structure: Neuroprotection or Misfolding Induction?

by Lidia Ciccone, Nicolò Tonali, William Shepard, Susanna Nencetti, Elisabetta Orlandini
Published 2021-03-01

The Positive Side of the Alzheimer’s Disease Amyloid Cross-Interactions: The Case of the Aβ 1-42 Peptide with Tau, TTR, CysC, and ApoA1

by Lidia Ciccone, Chenghui Shi, Davide di Lorenzo, Anne-Cécile Van Baelen, Nicolo Tonali
Published 2020-05-01

Multicomponent mixtures for cryoprotection and ligand solubilization

by Lidia Ciccone, Laura Vera, Livia Tepshi, Lea Rosalia, Armando Rossello, Enrico A. Stura
Published 2015-09-01

Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators

by Alessio Nocentini, Doretta Cuffaro, Lidia Ciccone, Elisabetta Orlandini, Susanna Nencetti, Elisa Nuti, Armando Rossello, Claudiu T. Supuran
Published 2021-01-01

Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide

by Salvatore Santamaria, Doretta Cuffaro, Elisa Nuti, Lidia Ciccone, Tiziano Tuccinardi, Francesca Liva, Felicia D’Andrea, Rens de Groot, Armando Rossello, Josefin Ahnström
Published 2021-01-01

Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity

by Felicia D'Andrea, Stefania Sartini, Ilaria Piano, Matteo Franceschi, Luca Quattrini, Lorenzo Guazzelli, Lidia Ciccone, Elisabetta Orlandini, Claudia Gargini, Concettina La Motta, Susanna Nencetti
Published 2020-01-01

Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines

by Susanna Nencetti, Doretta Cuffaro, Elisa Nuti, Lidia Ciccone, Armando Rossello, Marina Fabbi, Flavio Ballante, Gabriella Ortore, Grazia Carbotti, Francesco Campelli, Irene Banti, Rosaria Gangemi, Garland R. Marshall, Elisabetta Orlandini
Published 2021-01-01