Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of...

by Petra Simic, Xavier Fernando Vela Parada, Samir M. Parikh, Ryan Dellinger, Leonard P. Guarente, Eugene P. Rhee
Published 2020-08-01

Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice.

by Hideki Hayashi, Deya Cherpokova, Kimberly Martinod, Thilo Witsch, Siu Ling Wong, Maureen Gallant, Stephen M Cifuni, Leonard P Guarente, Denisa D Wagner
Published 2017-01-01

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.

by Ron Firestein, Gil Blander, Shaday Michan, Philipp Oberdoerffer, Shuji Ogino, Jennifer Campbell, Anupama Bhimavarapu, Sandra Luikenhuis, Rafael de Cabo, Charles Fuchs, William C Hahn, Leonard P Guarente, David A Sinclair
Published 2008-04-01

UTH1 and the genetic control of aging in the yeast, Saccharomyces

by Austriaco, Nicanor Robles, 1968-
Published 2007