A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase.

by Zack W Jones, Rachel Leander, Vito Quaranta, Leonard A Harris, Darren R Tyson
Published 2018-01-01

Exact hybrid particle/population simulation of rule-based models of biochemical systems.

by Justin S Hogg, Leonard A Harris, Lori J Stover, Niketh S Nair, James R Faeder
Published 2014-04-01

Unsupervised logic-based mechanism inference for network-driven biological processes.

by Martina Prugger, Lukas Einkemmer, Samantha P Beik, Perry T Wasdin, Leonard A Harris, Carlos F Lopez
Published 2021-06-01

An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability.

by Corey E Hayford, Darren R Tyson, C Jack Robbins, Peter L Frick, Vito Quaranta, Leonard A Harris
Published 2021-06-01

Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective.

by Julia Chifman, Seda Arat, Zhiyong Deng, Erica Lemler, James C Pino, Leonard A Harris, Michael A Kochen, Carlos F Lopez, Steven A Akman, Frank M Torti, Suzy V Torti, Reinhard Laubenbacher
Published 2017-02-01