Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability

by Leon Y Chan, Christopher F Mugler, Stephanie Heinrich, Pascal Vallotton, Karsten Weis
Published 2018-09-01

ATPase activity of the DEAD-box protein Dhh1 controls processing body formation

by Christopher Frederick Mugler, Maria Hondele, Stephanie Heinrich, Ruchika Sachdev, Pascal Vallotton, Adriana Y Koek, Leon Y Chan, Karsten Weis
Published 2016-10-01

Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells

by Ina Hollerer, Juliet C. Barker, Victoria Jorgensen, Amy Tresenrider, Claire Dugast-Darzacq, Leon Y. Chan, Xavier Darzacq, Robert Tjian, Elçin Ünal, Gloria A. Brar
Published 2019-04-01

Tunable Transcriptional Interference at the Endogenous Alcohol Dehydrogenase Gene Locus in Drosophila melanogaster

by Victoria Jorgensen, Jingxun Chen, Helen Vander Wende, Devon E. Harris, Alicia McCarthy, Shane Breznak, Siu Wah Wong-Deyrup, Yuzhang Chen, Prashanth Rangan, Gloria Ann Brar, Eric M. Sawyer, Leon Y. Chan, Elçin Ünal
Published 2020-05-01