Best Practices and Progress in Precision-Cut Liver Slice Cultures

by Liza Dewyse, Hendrik Reynaert, Leo A. van Grunsven
Published 2021-07-01

P311, Friend, or Foe of Tissue Fibrosis?

by Leslie Stradiot, Inge Mannaerts, Leo A. van Grunsven
Published 2018-10-01

The miRFIB-Score: A Serological miRNA-Based Scoring Algorithm for the Diagnosis of Significant Liver Fibrosis

by Joeri Lambrecht, Stefaan Verhulst, Hendrik Reynaert, Leo A. van Grunsven
Published 2019-08-01

The role of miRNAs in stress-responsive hepatic stellate cells during liver fibrosis

by Joeri eLambrecht, Inge eMannaerts, Leo A van Grunsven
Published 2015-07-01

Meta-Analysis of Human and Mouse Biliary Epithelial Cell Gene Profiles

by Stefaan Verhulst, Tania Roskams, Pau Sancho-Bru, Leo A. van Grunsven
Published 2019-09-01

Foreskin-derived mesenchymal stromal cells with aldehyde dehydrogenase activity: isolation and gene profiling

by Mehdi Najar, Emerence Crompot, Leo A. van Grunsven, Laurent Dollé, Laurence Lagneaux
Published 2018-04-01

Gene expression profiling of early hepatic stellate cell activation reveals a role for Igfbp3 in cell migration.

by Inge Mannaerts, Ben Schroyen, Stefaan Verhulst, Leentje Van Lommel, Frans Schuit, Marc Nyssen, Leo A van Grunsven
Published 2013-01-01

Efficient definitive endoderm induction from mouse embryonic stem cell adherent cultures: A rapid screening model for differentiation studies

by Josué Kunjom Mfopou, Marloes Geeraerts, Roba Dejene, Stijn Van Langenhoven, Asma Aberkane, Leo A. Van Grunsven, Luc Bouwens
Published 2014-01-01

A PDGFRβ-based score predicts significant liver fibrosis in patients with chronic alcohol abuse, NAFLD and viral liver diseaseResearch in context

by Joeri Lambrecht, Stefaan Verhulst, Inge Mannaerts, Jan-Peter Sowa, Jan Best, Ali Canbay, Hendrik Reynaert, Leo A. van Grunsven
Published 2019-05-01

Class II HDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29.

by Inge Mannaerts, Nathalie Eysackers, Oscar O Onyema, Katrien Van Beneden, Sergio Valente, Antonello Mai, Margarete Odenthal, Leo A van Grunsven
Published 2013-01-01

Comparison of the <i>Opn-CreER</i> and <i>Ck19-CreER</i> Drivers in Bile Ducts of Normal and Injured Mouse Livers

by Bram Lesaffer, Elisabeth Verboven, Leen Van Huffel, Iván M. Moya, Leo A. van Grunsven, Isabelle A. Leclercq, Frédéric P. Lemaigre, Georg Halder
Published 2019-04-01

Role of liver progenitors in acute liver injury

by Jan eBest, Jan eBest, Laurent eDollé, Paul eManka, Jason eCoombes, Leo A. van Grunsven, Wing-Kin eSyn
Published 2013-09-01

Modulation of the Unfolded Protein Response by Tauroursodeoxycholic Acid Counteracts Apoptotic Cell Death and Fibrosis in a Mouse Model for Secondary Biliary Liver Fibrosis

by Annelies Paridaens, Sarah Raevens, Lindsey Devisscher, Eliene Bogaerts, Xavier Verhelst, Anne Hoorens, Hans Van Vlierberghe, Leo A. van Grunsven, Anja Geerts, Isabelle Colle
Published 2017-01-01

Hepatic Stellate Cells Improve Engraftment of Human Primary Hepatocytes: A Preclinical Transplantation Study in an Animal Model

by Ange-Clarisse Dusabineza, Mustapha Najimi, Noémi Van Hul, Vanessa Legry, Dung Ngoc Khuu, Leo A. Van Grunsven, Etienne Sokal, Isabelle A. Leclercq M.D., Ph.D.
Published 2015-12-01

Time-dependent effect of hypoxia on tumor progression and liver progenitor cell markers in primary liver tumors.

by Eliene Bogaerts, Femke Heindryckx, Lindsey Devisscher, Annelies Paridaens, Yves-Paul Vandewynckel, Anja Van den Bussche, Xavier Verhelst, Louis Libbrecht, Leo A van Grunsven, Anja Geerts, Hans Van Vlierberghe
Published 2015-01-01

Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies.

by Jan Best, Stefaan Verhulst, Wing-Kin Syn, Kimberly Lagaisse, Noemi van Hul, Femke Heindryckx, Jan-Peter Sowa, Liesbeth Peeters, Hans Van Vlierberghe, Isabelle A Leclercq, Ali Canbay, Laurent Dollé, Leo A van Grunsven
Published 2016-01-01

PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells

by Jonathan De Smedt, Elise Anne van Os, Irene Talon, Sreya Ghosh, Burak Toprakhisar, Rodrigo Furtado Madeiro Da Costa, Samantha Zaunz, Marta Aguirre Vazquez, Ruben Boon, Pieter Baatsen, Ayla Smout, Stefaan Verhulst, Leo A. van Grunsven, Catherine M. Verfaillie
Published 2021-01-01