Class (I) Phosphoinositide 3-Kinases in the Tumor Microenvironment

by David Gyori, Tamara Chessa, Phillip T. Hawkins, Len R. Stephens
Published 2017-03-01

BMX Acts Downstream of PI3K to Promote Colorectal Cancer Cell Survival and Pathway Inhibition Sensitizes to the BH3 Mimetic ABT-737

by Danielle S. Potter, Paul Kelly, Olive Denneny, Veronique Juvin, Len R. Stephens, Caroline Dive, Christopher J. Morrow
Published 2014-02-01

Lysophosphatidylinositol-acyltransferase-1 (LPIAT1) is required to maintain physiological levels of PtdIns and PtdInsP(2) in the mouse.

by Karen E Anderson, Anna Kielkowska, Tom N Durrant, Veronique Juvin, Jonathan Clark, Len R Stephens, Phillip T Hawkins
Published 2013-01-01

PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4+ T Cells

by Daisy H. Luff, Katarzyna Wojdyla, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T. Hawkins, Len R. Stephens, Simon T. Barry, Klaus Okkenhaug
Published 2021-03-01

Signaling via class IA Phosphoinositide 3-kinases (PI3K) in human, breast-derived cell lines.

by Veronique Juvin, Mouhannad Malek, Karen E Anderson, Carine Dion, Tamara Chessa, Charlotte Lecureuil, G John Ferguson, Sabina Cosulich, Phillip T Hawkins, Len R Stephens
Published 2013-01-01

Use of the GRP1 PH domain as a tool to measure the relative levels of PtdIns(3,4,5)P3 through a protein-lipid overlay approach

by Hervé Guillou, Charlotte Lécureuil, Karen E. Anderson, Sabine Suire, G. John Ferguson, Chris D. Ellson, Alexander Gray, Nullin Divecha, Phillip T. Hawkins, Len R. Stephens
Published 2007-03-01