Cross-Species Transmission and Evolution of SIV Chimpanzee Progenitor Viruses Toward HIV-1 in Humanized Mice

by Kimberly Schmitt, James Curlin, Leila Remling-Mulder, Ryan Moriarty, Kelly Goff, Shelby O’Connor, Mark Stenglein, Preston Marx, Preston Marx, Ramesh Akkina
Published 2020-08-01

Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes.

by Ramesh Akkina, Bradford K Berges, Brent E Palmer, Leila Remling, C Preston Neff, Jes Kuruvilla, Elizabeth Connick, Joy Folkvord, Kathy Gagliardi, Afework Kassu, Sarah R Akkina
Published 2011-01-01