Updates in Anthracycline-Mediated Cardiotoxicity

by Canan G. Nebigil, Laurent Désaubry
Published 2018-11-01

Stereoselective Four-Component Synthesis of Functionalized 2,3-Dihydro-4-Nitropyrroles

by Dong Wang, Xinyue Ma, Linru Dong, Hairong Feng, Peng Yu, Laurent Désaubry, Laurent Désaubry
Published 2019-11-01

Novel carbocationic rearrangements of 1-styrylpropargyl alcohols

by Christine Basmadjian, Fan Zhang, Laurent Désaubry
Published 2015-06-01

Targeting GPCRs Against Cardiotoxicity Induced by Anticancer Treatments

by Anais Audebrand, Laurent Désaubry, Canan G. Nebigil
Published 2020-01-01

Updates on Anticancer Therapy-Mediated Vascular Toxicity and New Horizons in Therapeutic Strategies

by Po-Yen Hsu, Aynura Mammadova, Nadia Benkirane-Jessel, Laurent Désaubry, Canan G. Nebigil
Published 2021-07-01

Flavaglines alleviate doxorubicin cardiotoxicity: implication of Hsp27.

by Yohann Bernard, Nigel Ribeiro, Frédéric Thuaud, Gülen Türkeri, Ronan Dirr, Mounia Boulberdaa, Canan G Nebigil, Laurent Désaubry
Published 2011-01-01

FL3, a Synthetic Flavagline and Ligand of Prohibitins, Protects Cardiomyocytes via STAT3 from Doxorubicin Toxicity.

by Rehana Qureshi, Onur Yildirim, Adeline Gasser, Christine Basmadjian, Qian Zhao, Jean-Philippe Wilmet, Laurent Désaubry, Canan G Nebigil
Published 2015-01-01

Discovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1.

by Adeline Gasser, Simone Brogi, Kyoji Urayama, Toshishide Nishi, Hitoshi Kurose, Andrea Tafi, Nigel Ribeiro, Laurent Désaubry, Canan G Nebigil
Published 2015-01-01

Correction to: Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway

by Gangjun Yuan, Xin Chen, Zhuowei Liu, Wensu Wei, Qinghai Shu, Hussein Abou-Hamdan, Lijuan Jiang, Xiangdong Li, Rixin Chen, Laurent Désaubry, Fangjian Zhou, Dan Xie
Published 2021-03-01

Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway

by Gangjun Yuan, Xin Chen, Zhuowei Liu, Wensu Wei, Qinghai Shu, Hussein Abou-Hamdan, Lijuan Jiang, Xiangdong Li, Rixin Chen, Laurent Désaubry, Fangjian Zhou, Dan Xie
Published 2018-02-01

Prohibitin (PHB) expression is associated with aggressiveness in DLBCL and flavagline-mediated inhibition of cytoplasmic PHB functions induces anti-tumor effects

by Hafidha Bentayeb, Marine Aitamer, Barbara Petit, Lydie Dubanet, Sabria Elderwish, Laurent Désaubry, Armand de Gramont, Eric Raymond, Agnès Olivrie, Julie Abraham, Marie-Odile Jauberteau, Danielle Troutaud
Published 2019-11-01

Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity.

by Maxime G Blanchard, Jeroen H F de Baaij, Sjoerd A J Verkaart, Anke L Lameris, Christine Basmadjian, Qian Zhao, Laurent Désaubry, René J M Bindels, Joost G J Hoenderop
Published 2015-01-01

Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes

by Ezeddine Harmouch, Joseph Seitlinger, Hassan Chaddad, Geneviève Ubeaud-Sequier, Jochen Barths, Sani Saidu, Laurent Désaubry, Stéphanie Grandemange, Thierry Massfelder, Guy Fuhrmann, Florence Fioretti, Monique Dontenwill, Nadia Benkirane-Jessel, Ysia Idoux-Gillet
Published 2020-08-01

CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts

by Ricardos Tabet, Laure Schaeffer, Fernande Freyermuth, Melanie Jambeau, Michael Workman, Chao-Zong Lee, Chun-Chia Lin, Jie Jiang, Karen Jansen-West, Hussein Abou-Hamdan, Laurent Désaubry, Tania Gendron, Leonard Petrucelli, Franck Martin, Clotilde Lagier-Tourenne
Published 2018-01-01

An epitranscriptomic mechanism underlies selective mRNA translation remodelling in melanoma persister cells

by Shensi Shen, Sara Faouzi, Amandine Bastide, Sylvain Martineau, Hélène Malka-Mahieu, Yu Fu, Xiaoxiao Sun, Christine Mateus, Emilie Routier, Severine Roy, Laurent Desaubry, Fabrice André, Alexander Eggermont, Alexandre David, Jean-Yves Scoazec, Stéphan Vagner, Caroline Robert
Published 2019-12-01

Prokineticin Receptor-1 Signaling Inhibits Dose- and Time-Dependent Anthracycline-Induced Cardiovascular Toxicity Via Myocardial and Vascular Protection

by Adeline Gasser, PhD, Yu-Wen Chen, MD, PhD, Anais Audebrand, MSci, Ayhan Daglayan, MSci, Marine Charavin, PhD, Brigitte Escoubet, MD, PhD, Pavel Karpov, PhD, Igor Tetko, PhD, Michael W.Y. Chan, PhD, Daniela Cardinale, MD, PhD, Laurent Désaubry, PhD, Canan G. Nebigil, PharmD, PhD
Published 2019-09-01