Haemophilus influenzae and oxidative stress

by Alistair eHarrison, Lauren O. Bakaletz, Lauren O. Bakaletz, Lauren O. Bakaletz, Robert S. Munson, Robert S. Munson
Published 2012-03-01

The multifunctional host defense peptide SPLUNC1 is critical for homeostasis of the mammalian upper airway.

by Glen McGillivary, Lauren O Bakaletz
Published 2010-10-01

Nontypeable Haemophilus influenzae Responds to Virus-Infected Cells with a Significant Increase in Type IV Pilus Expression

by Elaine M. Mokrzan, Kolapo A. Dairo, Laura A. Novotny, Lauren O. Bakaletz
Published 2020-05-01

Monoclonal antibodies against DNA-binding tips of DNABII proteins disrupt biofilms in vitro and induce bacterial clearance in vivo

by Laura A. Novotny, Joseph A. Jurcisek, Steven D. Goodman, Lauren O. Bakaletz
Published 2016-08-01

Antibodies against the Majority Subunit (PilA) of the Type IV Pilus of Nontypeable Haemophilus influenzae Disperse Moraxella catarrhalis from a Dual-Species Biofilm

by Elaine M. Mokrzan, Laura A. Novotny, Kenneth L. Brockman, Lauren O. Bakaletz
Published 2018-12-01

Immunization with a Biofilm-Disrupting Nontypeable Haemophilus influenzae Vaccine Antigen Did Not Alter the Gut Microbiome in Chinchillas, Unlike Oral Delivery of a Broad-Spectrum...

by Michael T. Bailey, Christian L. Lauber, Laura A. Novotny, Steven D. Goodman, Lauren O. Bakaletz
Published 2020-04-01

Copy number variation of the beta defensin gene cluster on chromosome 8p influences the bacterial microbiota within the nasopharynx of otitis-prone children.

by Eric A Jones, Anchasa Kananurak, Charles L Bevins, Edward J Hollox, Lauren O Bakaletz
Published 2014-01-01

Structural stability of Burkholderia cenocepacia biofilms is reliant on eDNA structure and presence of a bacterial nucleic acid binding protein.

by Laura A Novotny, Amal O Amer, M Elizabeth Brockson, Steven D Goodman, Lauren O Bakaletz
Published 2013-01-01

Respiratory syncytial virus promotes Moraxella catarrhalis-induced ascending experimental otitis media.

by M Elizabeth Brockson, Laura A Novotny, Joseph A Jurcisek, Glen McGillivary, Martha R Bowers, Lauren O Bakaletz
Published 2012-01-01

Extracellular DNA and Type IV Pilus Expression Regulate the Structure and Kinetics of Biofilm Formation by Nontypeable Haemophilus influenzae

by Jayajit Das, Elaine Mokrzan, Vinal Lakhani, Lucia Rosas, Joseph A. Jurcisek, William C. Ray, Lauren O. Bakaletz, Matthew R. Parsek
Published 2017-12-01

The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media

by Luke V. Blakeway, Aimee Tan, Joseph A. Jurcisek, Lauren O. Bakaletz, John M. Atack, Ian R. Peak, Kate L. Seib
Published 2019-12-01

Nontypeable Haemophilus influenzae newly released (NRel) from biofilms by antibody-mediated dispersal versus antibody-mediated disruption are phenotypically distinct

by Elaine M. Mokrzan, Christian P. Ahearn, John R. Buzzo, Laura A. Novotny, Yan Zhang, Steven D. Goodman, Lauren O. Bakaletz
Published 2020-12-01

Selection for phase variation of LOS biosynthetic genes frequently occurs in progression of non-typeable Haemophilus influenzae infection from the nasopharynx to the middle ear of...

by Kate L Fox, John M Atack, Yogitha N Srikhanta, Anja Eckert, Laura A Novotny, Lauren O Bakaletz, Michael P Jennings
Published 2014-01-01

The ModA2 Phasevarion of nontypeable Haemophilus influenzae Regulates Resistance to Oxidative Stress and Killing by Human Neutrophils

by Kenneth L. Brockman, M. Taylor Branstool, John M. Atack, Frank Robledo-Avila, Santiago Partida-Sanchez, Michael P. Jennings, Lauren O. Bakaletz
Published 2017-06-01

Enhanced biofilm and extracellular matrix production by chronic carriage versus acute isolates of Salmonella Typhi.

by Aishwarya Devaraj, Juan F González, Bradley Eichar, Gatan Thilliez, Robert A Kingsley, Stephen Baker, Marc W Allard, Lauren O Bakaletz, John S Gunn, Steven D Goodman
Published 2021-01-01

Epigenetic Regulation Alters Biofilm Architecture and Composition in Multiple Clinical Isolates of Nontypeable Haemophilus influenzae

by Kenneth L. Brockman, Patrick N. Azzari, M. Taylor Branstool, John M. Atack, Benjamin L. Schulz, Freda E.-C. Jen, Michael P. Jennings, Lauren O. Bakaletz
Published 2018-09-01

Differences in Pneumococcal and Haemophilus influenzae Natural Antibody Development in Papua New Guinean Children in the First Year of Life

by Kelly M. Martinovich, Tasmina Rahman, Tasmina Rahman, Camilla de Gier, Camilla de Gier, Elke J. Seppanen, Tilda Orami, Caitlyn M. Granland, Jacinta Francis, Mition Yoannes, Karli J. Corscadden, Rebecca Ford, Peter Jacoby, Anita H. J. van den Biggelaar, Anita H. J. van den Biggelaar, Lauren O. Bakaletz, Allan W. Cripps, Deborah Lehmann, Deborah Lehmann, Peter C. Richmond, Peter C. Richmond, William S. Pomat, William S. Pomat, Lea-Ann S. Kirkham, Lea-Ann S. Kirkham, Ruth B. Thornton, Ruth B. Thornton
Published 2021-08-01