Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity

by Laura Casares, Juan Diego Unciti-Broceta, Maria Eugenia Prados, Diego Caprioglio, Daiana Mattoteia, Maureen Higgins, Giovanni Apendino, Albena T. Dinkova-Kostova, Eduardo Muñoz, Laureano de la Vega
Published 2020-10-01

Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1

by Laura Casares, Víctor García, Martín Garrido-Rodríguez, Estrella Millán, Juan A. Collado, Adela García-Martín, Jon Peñarando, Marco A. Calzado, Laureano de la Vega, Eduardo Muñoz
Published 2020-01-01

TRAF6 Phosphorylation Prevents Its Autophagic Degradation and Re-Shapes LPS-Triggered Signaling Networks

by Julia Busch, Rita Moreno, Laureano de la Vega, Vera Vivian Saul, Susanne Bacher, Felix von Zweydorf, Marius Ueffing, Axel Weber, Christian Johannes Gloeckner, Uwe Linne, Michael Kracht, Michael Lienhard Schmitz
Published 2021-07-01

Downregulation of Keap1 Confers Features of a Fasted Metabolic State

by Elena V. Knatko, Michael H. Tatham, Ying Zhang, Cecilia Castro, Maureen Higgins, Sharadha Dayalan Naidu, Chiara Leonardi, Laureano de la Vega, Tadashi Honda, Julian L. Griffin, Ronald T. Hay, Albena T. Dinkova-Kostova
Published 2020-10-01

High NRF2 Levels Correlate with Poor Prognosis in Colorectal Cancer Patients and with Sensitivity to the Kinase Inhibitor AT9283 In Vitro

by Laura Torrente, Gunjit Maan, Asma Oumkaltoum Rezig, Jean Quinn, Angus Jackson, Andrea Grilli, Laura Casares, Ying Zhang, Evgeny Kulesskiy, Jani Saarela, Silvio Bicciato, Joanne Edwards, Albena T. Dinkova-Kostova, Laureano de la Vega
Published 2020-09-01