Development of Anthraquinone Derivatives as Ectonucleoside Triphosphate Diphosphohydrolase (NTPDase) Inhibitors With Selectivity for NTPDase2 and NTPDase3

by Younis Baqi, Mahmoud Rashed, Laura Schäkel, Enas M. Malik, Julie Pelletier, Jean Sévigny, Jean Sévigny, Amelie Fiene, Christa E. Müller
Published 2020-08-01

Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39

by Vittoria Lopez, Laura Schäkel, H. J. Maximilian Schuh, Michael S. Schmidt, Salahuddin Mirza, Christian Renn, Julie Pelletier, Sang-Yong Lee, Jean Sévigny, Susanne Alban, Gerd Bendas, Christa E. Müller
Published 2021-01-01

Nucleotide Analog ARL67156 as a Lead Structure for the Development of CD39 and Dual CD39/CD73 Ectonucleotidase Inhibitors

by Laura Schäkel, Constanze C. Schmies, Riham M. Idris, Xihuan Luo, Sang-Yong Lee, Vittoria Lopez, Salahuddin Mirza, The Hung Vu, Julie Pelletier, Jean Sévigny, Jean Sévigny, Vigneshwaran Namasivayam, Christa E. Müller
Published 2020-09-01