Targeting of GFP-Cre to the mouse Cyp11a1 locus both drives cre recombinase expression in steroidogenic cells and permits generation of Cyp11a1 knock out mice.

by Laura O'Hara, Jean Philippe York, Pumin Zhang, Lee B Smith
Published 2014-01-01

Modelling steroidogenesis: a framework model to support hypothesis generation and testing across endocrine studies

by Laura O’Hara, Peter J. O’Shaughnessy, Tom C. Freeman, Lee B. Smith
Published 2018-04-01

Pituitary androgen receptor signalling regulates prolactin but not gonadotrophins in the male mouse.

by Laura O'Hara, Michael Curley, Maria Tedim Ferreira, Lyndsey Cruickshanks, Laura Milne, Lee B Smith
Published 2015-01-01

LKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis.

by Fiona C Denison, Lee B Smith, Phillip J Muckett, Laura O'Hara, David Carling, Angela Woods
Published 2011-01-01

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity

by Anne-Louise Gannon, Anne-Louise Gannon, Laura O’Hara, Laura O’Hara, Ian J. Mason, Anne Jørgensen, Anne Jørgensen, Hanne Frederiksen, Hanne Frederiksen, Michael Curley, Laura Milne, Sarah Smith, Rod T. Mitchell, Lee B. Smith, Lee B. Smith
Published 2021-01-01

Androgen receptor expression is required to ensure development of adult Leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse tes...

by Peter J. O’Shaughnessy, Rod T. Mitchell, Ana Monteiro, Laura O’Hara, Lyndsey Cruickshanks, Hedi Claahsen-van der Grinten, Pamela Brown, Margaret Abel, Lee B. Smith
Published 2019-04-01

Low-dose tamoxifen treatment in juvenile males has long-term adverse effects on the reproductive system: implications for inducible transgenics

by Saloni H. Patel, Laura O’Hara, Nina Atanassova, Sarah E. Smith, Michael K. Curley, Diane Rebourcet, Annalucia L. Darbey, Anne-Louise Gannon, Richard M. Sharpe, Lee B. Smith
Published 2017-08-01

Modelling the Structure and Dynamics of Biological Pathways.

by Laura O'Hara, Alessandra Livigni, Thanos Theo, Benjamin Boyer, Tim Angus, Derek Wright, Sz-Hau Chen, Sobia Raza, Mark W Barnett, Paul Digard, Lee B Smith, Tom C Freeman
Published 2016-08-01