RNA disruption indicates CHOP therapy efficacy in canine lymphoma

by Amadeo M. Parissenti, Laura B. Pritzker, Baoqing Guo, Rashmi Narendrula, Shirly Xiaohui Wang, Lin Laura Lin, Jingchun Pei, Karolina Skowronski, Dorothee Bienzle, J. Paul Woods, Kenneth P. H. Pritzker, Brenda L. Coomber
Published 2019-12-01

Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design.

by James R Apgar, Amy S P Tam, Rhady Sorm, Sybille Moesta, Amy C King, Han Yang, Kerry Kelleher, Denise Murphy, Aaron M D'Antona, Guoying Yan, Xiaotian Zhong, Linette Rodriguez, Weijun Ma, Darren E Ferguson, Gregory J Carven, Eric M Bennett, Laura Lin
Published 2020-01-01

Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation

by Danna M. Breen, Srinath Jagarlapudi, Anita Patel, Chang Zou, Stephanie Joaquim, Xiangping Li, Liya Kang, Jincheng Pang, Katherine Hales, Enida Ziso-Qejvanaj, Nicholas B. Vera, Donald Bennett, Tao He, Matthew Lambert, Kerry Kelleher, Zhidan Wu, Bei B. Zhang, Laura Lin, Randy J. Seeley, Olivier Bezy
Published 2021-06-01

Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation

by Ella Fung, Liya Kang, Diana Sapashnik, Susan Benard, Annette Sievers, Yan Liu, Guoying Yan, Jing Zhou, Linette Rodriguez, Weijun Ma, Wayne R. Stochaj, Edward LaVallie, Liliana Wroblewska, Kerry Kelleher, Amy Tam, Olivier Bezy, Danna Breen, Jeffrey R. Chabot, Tao He, Laura Lin, Zhidan Wu, Lidia Mosyak
Published 2021-04-01

Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer

by Adam R. Root, Wei Cao, Bilian Li, Peter LaPan, Caryl Meade, Jocelyn Sanford, Macy Jin, Cliona O’Sullivan, Emma Cummins, Matthew Lambert, Alfredo D. Sheehan, Weijun Ma, Scott Gatto, Kelvin Kerns, Khetemenee Lam, Aaron M. D’Antona, Lily Zhu, William A. Brady, Susan Benard, Amy King, Tao He, Lisa Racie, Maya Arai, Dianah Barrett, Wayne Stochaj, Edward R. LaVallie, James R. Apgar, Kristine Svenson, Lidia Mosyak, Yinhua Yang, Gurunadh R. Chichili, Liqin Liu, Hua Li, Steve Burke, Syd Johnson, Ralph Alderson, William J. J. Finlay, Laura Lin, Stéphane Olland, William Somers, Ezio Bonvini, Hans-Peter Gerber, Chad May, Paul A. Moore, Lioudmila Tchistiakova, Laird Bloom
Published 2016-03-01