Reduction of Leukocyte Microvascular Adherence and Preservation of Blood-Brain Barrier Function by Superoxide-Lowering Therapies in a Piglet Model of Neonatal Asphyxia

by Jacob B. Ruden, Kevin L. Quick, Ernesto R. Gonzales, Aarti R. Shah, Aarti R. Shah, T. S. Park, Nan Kennedy, Laura L. Dugan, Laura L. Dugan, Jeffrey M. Gidday
Published 2019-05-01

nNOS(+) striatal neurons, a subpopulation spared in Huntington Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic chall...

by Lorella M.T. Canzoniero, Alberto eGranzotto, Dorothy M Turetsky, Dennis W Choi, Laura L Dugan, Laura L Dugan, Stefano L Sensi, Stefano L Sensi, Stefano L Sensi
Published 2013-05-01

Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage.

by Sameh S Ali, Mary Hsiao, Huiwen W Zhao, Laura L Dugan, Gabriel G Haddad, Dan Zhou
Published 2012-01-01

Buckminsterfullerenol Free Radical Scavengers Reduce Excitotoxic and Apoptotic Death of Cultured Cortical Neurons

by Laura L. Dugan, Joseph K. Gabrielsen, Shan P. Yu, Tien-Sung Lin, Dennis W. Choi
Published 1996-04-01

IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase.

by Laura L Dugan, Sameh S Ali, Grigoriy Shekhtman, Amanda J Roberts, Jacinta Lucero, Kevin L Quick, M Margarita Behrens
Published 2009-01-01

The Estrogen Receptor Is Not Essential for All Estrogen Neuroprotection: New Evidence from a New Analog

by Shuli Xia, Zu Yun Cai, Liu Lin Thio, Jeong Sook Kim-Han, Laura L. Dugan, Douglas F. Covey, Steven M. Rothman
Published 2002-04-01

Antipurinergic therapy corrects the autism-like features in the poly(IC) mouse model.

by Robert K Naviaux, Zarazuela Zolkipli, Lin Wang, Tomohiro Nakayama, Jane C Naviaux, Thuy P Le, Michael A Schuchbauer, Mihael Rogac, Qingbo Tang, Laura L Dugan, Susan B Powell
Published 2013-01-01