Mesodiencephalic dopaminergic neuronal differentiation does not involve GLI2A-mediated SHH-signaling and is under the direct influence of canonical WNT signaling.

by Simone Mesman, Lars von Oerthel, Marten P Smidt
Published 2014-01-01

Pitx3 and En1 determine the size and molecular programming of the dopaminergic neuronal pool.

by Willemieke M Kouwenhoven, Lars von Oerthel, Marten P Smidt
Published 2017-01-01

EZH2 Influences mdDA Neuronal Differentiation, Maintenance and Survival

by Iris Wever, Lars von Oerthel, Cindy M. R. J. Wagemans, Marten P. Smidt
Published 2019-01-01

Phox2b influences the development of a caudal dopaminergic subset.

by Elisa J Hoekstra, Lars von Oerthel, Annemarie J A van der Linden, Marten P Smidt
Published 2012-01-01

Molecular marker differences relate to developmental position and subsets of mesodiencephalic dopaminergic neurons.

by Simone M Smits, Lars von Oerthel, Elisa J Hoekstra, J Peter H Burbach, Marten P Smidt
Published 2013-01-01

Spatial and temporal lineage analysis of a Pitx3-driven Cre-recombinase knock-in mouse model.

by Marten P Smidt, Lars von Oerthel, Elisa J Hoekstra, Raymond D Schellevis, Marco F M Hoekman
Published 2012-01-01

Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development

by Koushik Chakrabarty, Lars Von Oerthel, Anita Hellemons, Frédéric Clotman, Agnès Espana, Marian Groot Koerkamp, Frank C. P. Holstege, R. Jeroen Pasterkamp, Marten P. Smidt
Published 2012-05-01

Lmx1a encodes a rostral set of mesodiencephalic dopaminergic neurons marked by the Wnt/B-catenin signaling activator R-spondin 2.

by Elisa J Hoekstra, Lars von Oerthel, Lars P van der Heide, Willemieke M Kouwenhoven, Jesse V Veenvliet, Iris Wever, Yong-Ri Jin, Jeong K Yoon, Annemarie J A van der Linden, Frank C P Holstege, Marian J Groot Koerkamp, Marten P Smidt
Published 2013-01-01

miR-34b/c Regulates Wnt1 and Enhances Mesencephalic Dopaminergic Neuron Differentiation

by Roberto De Gregorio, Salvatore Pulcrano, Claudia De Sanctis, Floriana Volpicelli, Ezia Guatteo, Lars von Oerthel, Emanuele Claudio Latagliata, Roberta Esposito, Rosa Maria Piscitelli, Carla Perrone-Capano, Valerio Costa, Dario Greco, Stefano Puglisi-Allegra, Marten P. Smidt, Umberto di Porzio, Massimiliano Caiazzo, Nicola Biagio Mercuri, Meng Li, Gian Carlo Bellenchi
Published 2018-04-01

Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

by James D. Mills, Anand M. Iyer, Jackelien van Scheppingen, Anika Bongaarts, Jasper J. Anink, Bart Janssen, Till S. Zimmer, Wim G. Spliet, Peter C. van Rijen, Floor E. Jansen, Martha Feucht, Johannes A. Hainfellner, Pavel Krsek, Josef Zamecnik, Katarzyna Kotulska, Sergiusz Jozwiak, Anna Jansen, Lieven Lagae, Paolo Curatolo, David J. Kwiatkowski, R. Jeroen Pasterkamp, Ketharini Senthilkumar, Lars von Oerthel, Marco F. Hoekman, Jan A. Gorter, Peter B. Crino, Angelika Mühlebner, Brendon P. Scicluna, Eleonora Aronica
Published 2017-08-01