Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two steps.

by Ladislav Bumba, Jiri Masin, Radovan Fiser, Peter Sebo
Published 2010-05-01

Bordetella Pertussis Adenylate Cyclase Toxin Does Not Possess a Phospholipase A Activity; Serine 606 and Aspartate 1079 Residues Are Not Involved in Target Cell Delivery of the Ade...

by Ladislav Bumba, Jiri Masin, Adriana Osickova, Radim Osicka, Peter Sebo
Published 2018-06-01

Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3

by Radim Osicka, Adriana Osickova, Shakir Hasan, Ladislav Bumba, Jiri Cerny, Peter Sebo
Published 2015-12-01

Poly-N-Acetyllactosamine Neo-Glycoproteins as Nanomolar Ligands of Human Galectin-3: Binding Kinetics and Modeling

by Ladislav Bumba, Dominic Laaf, Vojtěch Spiwok, Lothar Elling, Vladimír Křen, Pavla Bojarová
Published 2018-01-01

Integrative binding sites within intracellular termini of TRPV1 receptor.

by Lenka Grycova, Blanka Holendova, Ladislav Bumba, Jan Bily, Michaela Jirku, Zdenek Lansky, Jan Teisinger
Published 2012-01-01

Structure–Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes

by Jakub Novak, Ondrej Cerny, Adriana Osickova, Irena Linhartova, Jiri Masin, Ladislav Bumba, Peter Sebo, Radim Osicka
Published 2017-09-01

Acellular Pertussis Vaccine Inhibits <i>Bordetella pertussis</i> Clearance from the Nasal Mucosa of Mice

by Jana Holubová, Ondřej Staněk, Ludmila Brázdilová, Jiří Mašín, Ladislav Bumba, Andrew R. Gorringe, Frances Alexander, Peter Šebo
Published 2020-11-01

Structural Basis of Ca2+-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins

by Vojtech Kuban, Pavel Macek, Jozef Hritz, Katerina Nechvatalova, Katerina Nedbalcova, Martin Faldyna, Peter Sebo, Lukas Zidek, Ladislav Bumba
Published 2020-03-01

Production of Highly Active Recombinant Dermonecrotic Toxin of <i>Bordetella Pertussis</i>

by Ondrej Stanek, Irena Linhartova, Jana Holubova, Ladislav Bumba, Zdenko Gardian, Anna Malandra, Barbora Bockova, Shihono Teruya, Yasuhiko Horiguchi, Radim Osicka, Peter Sebo
Published 2020-09-01

Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins

by Anna Lepesheva, Adriana Osickova, Jana Holubova, David Jurnecka, Sarka Knoblochova, Carlos Espinosa-Vinals, Ladislav Bumba, Karolina Skopova, Radovan Fiser, Radim Osicka, Peter Sebo, Jiri Masin
Published 2021-10-01

Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores.

by Radovan Fiser, Jiri Masin, Ladislav Bumba, Eva Pospisilova, Catherine Fayolle, Marek Basler, Lenka Sadilkova, Irena Adkins, Jana Kamanova, Jan Cerny, Ivo Konopasek, Radim Osicka, Claude Leclerc, Peter Sebo
Published 2012-01-01

Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells.

by Irena Adkins, Jana Kamanova, Aneta Kocourkova, Martina Svedova, Jakub Tomala, Hana Janova, Jiri Masin, Barbora Chladkova, Ladislav Bumba, Marek Kovar, Padraig J Ross, Ludmila Tuckova, Radek Spisek, Kingston H G Mills, Peter Sebo
Published 2014-01-01