Editorial: Cancer Metabolism: Current Knowledge and Perspectives

by Leonardo Freire-de-Lima, Lucia Mendonça-Previato, Luciana Boffoni Gentile
Published 2019-04-01

Editorial: Glycosylation Changes in Cancer: An Innovative Frontier at the Interface of Cancer and Glycobiology

by Leonardo Freire-De-Lima, Jose Osvaldo Previato, Lucia Mendonça-Previato
Published 2016-11-01

Resistance to paclitaxel induces glycophenotype changes and mesenchymal-to-epithelial transition activation in the human prostate cancer cell line PC-3

by Leonardo Marques da Fonseca, Danilo Macedo Calvalhan, Jose Osvaldo Previato, Lucia Mendonça Previato, Leonardo Freire-de-Lima
Published 2020-09-01

Intrinsic and Chemotherapeutic Stressors Modulate ABCC-Like Transport in <i>Trypanosoma cruzi</i>

by Kelli Monteiro da Costa, Eduardo J. Salustiano, Raphael do Carmo Valente, Leonardo Freire-de-Lima, Lucia Mendonça-Previato, José Osvaldo Previato
Published 2021-06-01

Functional Characterization of ABCC Proteins from Trypanosoma cruzi and Their Involvement with Thiol Transport

by Kelli Monteiro da Costa, Raphael C. Valente, Eduardo J. Salustiano, Luciana B. Gentile, Leonardo Freire-de-Lima, Lucia Mendonça-Previato, José O. Previato
Published 2018-02-01

Expanding the knowledge of the chemical structure of glycoconjugates from Trypanosoma cruzi TcI genotype. Contribution to taxonomic studies

by LEONARDO M. FONSECA, TATIANA C. GARCEZ, LUCIANA PENHA, LEONARDO FREIRE-DE-LIMA, EMMANUEL MAES, KELLI M. COSTA, LUCIA MENDONÇA-PREVIATO, JOSE O. PREVIATO
Published 2016-01-01

Increase of O-glycosylated oncofetal fibronectin in high glucose-induced epithelial-mesenchymal transition of cultured human epithelial cells.

by Frederico Alisson-Silva, Leonardo Freire-de-Lima, Joana L Donadio, Miguel C Lucena, Luciana Penha, Julliana N Sá-Diniz, Wagner B Dias, Adriane R Todeschini
Published 2013-01-01

Design, Synthesis and Trypanocidal Evaluation of Novel 1,2,4-Triazoles-3-thiones Derived from Natural Piperine

by Marco Edilson Freire de Lima, Lucia Mendonça-Previato, Rosane Nora Castro, Julliana de Nazareth Sá Diniz, José Osvaldo Previato, Leonardo Freire-de-Lima, Tatiany Nunes Franklim
Published 2013-05-01

Theft and Reception of Host Cell's Sialic Acid: Dynamics of Trypanosoma Cruzi Trans-sialidases and Mucin-Like Molecules on Chagas' Disease Immunomodulation

by Leonardo Marques da Fonseca, Kelli Monteiro da Costa, Victoria de Sousa Chaves, Célio Geraldo Freire-de-Lima, Alexandre Morrot, Alexandre Morrot, Lucia Mendonça-Previato, Jose Osvaldo Previato, Leonardo Freire-de-Lima
Published 2019-02-01

Multiple Myeloma Cells Express Key Immunoregulatory Cytokines and Modulate the Monocyte Migratory Response

by Leonardo Freire-de-Lima, Ana Flávia Fernandes Ribas Nardy, Erivan Schnaider Ramos-Junior, Luciana Conde, Jéssica Santos Lemos, Leonardo Marques da Fonseca, Juliana Echevarria Lima, Angelo Maiolino, Alexandre Morrot, Alexandre Morrot
Published 2017-06-01

Metabolic Symbiosis and Immunomodulation: How Tumor Cell-Derived Lactate May Disturb Innate and Adaptive Immune Responses

by Alexandre Morrot, Alexandre Morrot, Leonardo Marques da Fonseca, Eduardo J. Salustiano, Luciana Boffoni Gentile, Luciana Conde, Alessandra Almeida Filardy, Tatiany Nunes Franklim, Kelli Monteiro da Costa, Celio Geraldo Freire-de-Lima, Leonardo Freire-de-Lima
Published 2018-03-01

Immunomodulatory Role of Capsular Polysaccharides Constituents of Cryptococcus neoformans

by Debora Decote-Ricardo, Isabel Ferreira LaRocque-de-Freitas, Juliana Dutra B. Rocha, Danielle O. Nascimento, Danielle O. Nascimento, Marise P. Nunes, Alexandre Morrot, Alexandre Morrot, Leonardo Freire-de-Lima, Jose Osvaldo Previato, Lucia Mendonça-Previato, Celio Geraldo Freire-de-Lima
Published 2019-06-01

Targeting the Hexosamine Biosynthetic Pathway Prevents Plasmodium Developmental Cycle and Disease Pathology in Vertebrate Host

by Pollyanna Stephanie Gomes, Scott Tanghe, Julio Gallego-Delgado, Luciana Conde, Leonardo Freire-de-Lima, Ana Carolina Lima, Célio Geraldo Freire-de-Lima, Josué da Costa Lima Junior, Otacílio Moreira, Paulo Totino, Ana Rodriguez, Adriane Regina Todeschini, Alexandre Morrot, Alexandre Morrot
Published 2019-02-01

Role of Inactive and Active Trypanosoma cruzi Trans-sialidases on T Cell Homing and Secretion of Inflammatory Cytokines

by Leonardo Freire-de-Lima, Luciana B. Gentile, Leonardo M. da Fonseca, Kelli M. da Costa, Jessica Santos Lemos, Lucas Rodrigues Jacques, Alexandre Morrot, Alexandre Morrot, Célio G. Freire-de-Lima, Marise P. Nunes, Marise P. Nunes, Christina M. Takiya, Jose O. Previato, Lucia Mendonça-Previato
Published 2017-07-01

Inhibitory effects of Trypanosoma cruzi sialoglycoproteins on CD4+ T cells are associated with increased susceptibility to infection.

by Marise Pinheiro Nunes, Bárbara Fortes, João Luiz Silva-Filho, Eugênia Terra-Granado, Leonardo Santos, Luciana Conde, Isadora de Araújo Oliveira, Leonardo Freire-de-Lima, Marina Vieira Martins, Ana Acacia Sá Pinheiro, Christina Maeda Takyia, Célio Geraldo Freire-de-Lima, Adriane Regina Todeschini, George Alexandre Dosreis, Alexandre Morrot
Published 2013-01-01

Antibody Repertoires Identify β-Tubulin as a Host Protective Parasite Antigen in Mice Infected With Trypanosoma cruzi

by Fabricio Montalvão, Fabricio Montalvão, Danielle Oliveira Nascimento, Marise P. Nunes, Carolina M. Koeller, Alexandre Morrot, Alexandre Morrot, Leticia Miranda S. Lery, Paulo M. Bisch, Santuza M. R. Teixeira, Rita Vasconcellos, Leonardo Freire-de-Lima, Marcela F. Lopes, Norton Heise, George A. DosReis, Célio Geraldo Freire-de-Lima
Published 2018-04-01

NH36 and F3 Antigen-Primed Dendritic Cells Show Preserved Migrating Capabilities and CCR7 Expression and F3 Is Effective in Immunotherapy of Visceral Leishmaniasis

by Dirlei Nico, Fernanda Martins Almeida, Fernanda Martins Almeida, Juliana Maria Motta, Fellipe Soares dos Santos Cardoso, Celio Geraldo Freire-de-Lima, Leonardo Freire-de-Lima, Paula Melo de Luca, Ana Maria Blanco Martinez, Alexandre Morrot, Alexandre Morrot, Clarisa Beatriz Palatnik-de-Sousa, Clarisa Beatriz Palatnik-de-Sousa
Published 2018-05-01

Circulating Plasma MicroRNA-208a as Potential Biomarker of Chronic Indeterminate Phase of Chagas Disease

by Leandra Linhares-Lacerda, Leandra Linhares-Lacerda, Alessandra Granato, João Francisco Gomes-Neto, Luciana Conde, Leonardo Freire-de-Lima, Elisangela O. de Freitas, Celio G. Freire-de-Lima, Shana P. Coutinho Barroso, Rodrigo Jorge de Alcântara Guerra, Roberto C. Pedrosa, Wilson Savino, Wilson Savino, Alexandre Morrot, Alexandre Morrot
Published 2018-03-01

X-linked immunodeficient (XID) mice exhibit high susceptibility to Cryptococcus gattii infection

by Israel Diniz-Lima, Pablo Rodrigo da Rosa, Elias Barbosa da Silva-Junior, Joyce Cristina Guimarães-de-Oliveira, Elisangela Oliveira de Freitas, Danielle de Oliveira Nascimento, Alexandre Morrot, Leonardo Nimrichter, Jose Osvaldo Previato, Lucia Mendonça-Previato, Leonardo Freire-de-Lima, Debora Decote-Ricardo, Celio Geraldo Freire-de-Lima
Published 2021-09-01

Piperine Inhibits TGF-β Signaling Pathways and Disrupts EMT-Related Events in Human Lung Adenocarcinoma Cells

by Leonardo Marques da Fonseca, Lucas Rodrigues Jacques da Silva, Jhenifer Santos dos Reis, Marcos André Rodrigues da Costa Santos, Victoria de Sousa Chaves, Kelli Monteiro da Costa, Julliana de Nazareth Sa-Diniz, Celio Geraldo Freire de Lima, Alexandre Morrot, Tatiany Nunes Franklim, Douglas Chaves de Alcântara-Pinto, Marco Edilson Freire de Lima, Jose Osvaldo Previato, Lucia Mendonça-Previato, Leonardo Freire-de-Lima
Published 2020-04-01