Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CLpro) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates [version 1; p...

by Yu Wai Chen, Chin-Pang Bennu Yiu, Kwok-Yin Wong
Published 2020-02-01

Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CLpro) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates [version 2; p...

by Yu Wai Chen, Chin-Pang Bennu Yiu, Kwok-Yin Wong
Published 2020-04-01

Effect of Lactamase Inhibitors on the Biosensor Penp during the Measurement of Lactam Antibiotics Concentration

by Dagoberto Soto, Camila Silva, Cristian Ugalde, Kwok-Yin Wong, Yun-Chung Leung, Lok-Yan So, Max Andresen
Published 2019-03-01

BADAN-conjugated β-lactamases as biosensors for β-lactam antibiotic detection.

by Ho-Wah Au, Man-Wah Tsang, Yu Wai Chen, Pui-Kin So, Kwok-Yin Wong, Yun-Chung Leung
Published 2020-01-01

Plasma and Renal Cortex Meropenem Concentrations in Patients Undergoing Percutaneous Renal Biopsy

by Rodrigo A. Sepúlveda, Patricio Downey, Dagoberto Soto, Kwok-Yin Wong, Yun-Chung Leung, Lok-Yan So, Max Andresen
Published 2019-01-01

Efficient production of secretory Streptomyces clavuligerus β-lactamase inhibitory protein (BLIP) in Pichia pastoris

by Kin-Ho Law, Man-Wah Tsang, Yuk-Ki Wong, Ming-San Tsang, Pui-Yee Lau, Kwok-Yin Wong, Kwok-Ping Ho, Yun-Chung Leung
Published 2018-04-01

An antibacterial platform based on capacitive carbon-doped TiO2 nanotubes after direct or alternating current charging

by Guomin Wang, Hongqing Feng, Liangsheng Hu, Weihong Jin, Qi Hao, Ang Gao, Xiang Peng, Wan Li, Kwok-Yin Wong, Huaiyu Wang, Zhou Li, Paul K. Chu
Published 2018-05-01

Evaluation of Meropenem Pharmacokinetics in an Experimental Acute Respiratory Distress Syndrome (ARDS) Model during Extracorporeal Membrane Oxygenation (ECMO) by Using a PenP β-Lac...

by Max Andresen, Joaquin Araos, Kwok-Yin Wong, Yun-Chung Leung, Lok-Yan So, Wai-Ting Wong, Salvador Cabrera, Camila Silva, Leyla Alegria, Alejandro Bruhn, Dagoberto Soto
Published 2018-05-01

Method Based on the β-Lactamase PenPC Fluorescent Labeled for β-Lactam Antibiotic Quantification in Human Plasma

by Max Andresen, Kwok-Yin Wong, Yun-Chung Leung, Wai-Ting Wong, Pak-Ho Chan, Max Andresen-Vasquez, Leyla Alegria, Camila Silva, Pablo Tapia, Patricio Downey, Dagoberto Soto
Published 2016-01-01

Photocatalytic water splitting by N-TiO2 on MgO (111) with exceptional quantum efficiencies at elevated temperatures

by Yiyang Li, Yung-Kang Peng, Liangsheng Hu, Jianwei Zheng, Dharmalingam Prabhakaran, Simson Wu, Timothy J. Puchtler, Mo Li, Kwok-Yin Wong, Robert A. Taylor, Shik Chi Edman Tsang
Published 2019-09-01

A Thiazole Orange Derivative Targeting the Bacterial Protein FtsZ Shows Potent Antibacterial Activity

by Ning Sun, Yu-Jing Lu, Fung-Yi Chan, Ruo-Lan Du, Yuan-yuan Zheng, Kun Zhang, Lok-Yan So, Ruben Abagyan, Chao Zhuo, Yun-Chung Leung, Kwok-Yin Wong
Published 2017-05-01

Mono-PEGylation of a Thermostable Arginine-Depleting Enzyme for the Treatment of Lung Cancer

by Sai-Fung Chung, Chi-Fai Kim, Sui-Yi Kwok, Suet-Ying Tam, Yu Wai Chen, Hiu-Chi Chong, Siu-Lun Leung, Pui-Kin So, Kwok-Yin Wong, Yun-Chung Leung, Wai-Hung Lo
Published 2020-06-01

Antibacterial activity of 3-methylbenzo[d]thiazol-methylquinolinium derivatives and study of their action mechanism

by Ning Sun, Ruo-Lan Du, Yuan-Yuan Zheng, Qi Guo, Sen-Yuan Cai, Zhi-Hua Liu, Zhi-Yuan Fang, Wen-Chang Yuan, Ting Liu, Xiao-Mei Li, Yu-Jing Lu, Kwok-Yin Wong
Published 2018-01-01

Rational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activity.

by Ning Sun, Fung-Yi Chan, Yu-Jing Lu, Marco A C Neves, Hok-Kiu Lui, Yong Wang, Ka-Yan Chow, Kin-Fai Chan, Siu-Cheong Yan, Yun-Chung Leung, Ruben Abagyan, Tak-Hang Chan, Kwok-Yin Wong
Published 2014-01-01

Study of Benzofuroquinolinium Derivatives as a New Class of Potent Antibacterial Agent and the Mode of Inhibition Targeting FtsZ

by Yuan-Yuan Zheng, Yuan-Yuan Zheng, Ruo-Lan Du, Sen-Yuan Cai, Zhi-Hua Liu, Zhi-Yuan Fang, Ting Liu, Lok-Yan So, Yu-Jing Lu, Yu-Jing Lu, Ning Sun, Ning Sun, Ning Sun, Kwok-Yin Wong
Published 2018-08-01

Efficient Synthesis of Amine-Linked 2,4,6-Trisubstituted Pyrimidines as a New Class of Bacterial FtsZ Inhibitors

by Kin-Fai Chan, Ning Sun, Siu-Cheong Yan, Iris L. K. Wong, Hok-Kiu Lui, Kwan-Choi Cheung, Jian Yuan, Fung-Yi Chan, Zhiwei Zheng, Edward W. C. Chan, Sheng Chen, Yun-Chung Leung, Tak Hang Chan, Kwok-Yin Wong
Published 2017-10-01