AUY922 effectively overcomes MET- and AXL-mediated resistance to EGFR-TKI in lung cancer cells.

by Yun Jung Choi, Seon Ye Kim, Kwang Sup So, In-Jeoung Baek, Woo Sung Kim, Se Hoon Choi, Jae Cheol Lee, Trever G Bivona, Jin Kyung Rho, Chang-Min Choi
Published 2015-01-01

Autophagosome-mediated EGFR down-regulation induced by the CK2 inhibitor enhances the efficacy of EGFR-TKI on EGFR-mutant lung cancer cells with resistance by T790M.

by Kwang Sup So, Cheol Hyeon Kim, Jin Kyung Rho, Sun Ye Kim, Yun Jung Choi, Joon Seon Song, Woo Sung Kim, Chang Min Choi, Young Jin Chun, Jae Cheol Lee
Published 2014-01-01