BET bromodomain proteins regulate enhancer function during adipogenesis

by Brown, Jonathan D., Feldman, Zachary B., Doherty, Sean P., Reyes, Jaime M., Rahl, Peter B., Lin, Charles Y., Sheng, Quanhu, Duan, Qiong, Federation, Alexander J., Kung, Andrew L., Haldar, Saptarsi M., Plutzky, Jorge, Bradner, James E., Young, Richard A.
Published 2018

SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia

by Puissant, Alexandre, Alexe, Gabriela, Pikman, Yana, Bassil, Christopher F, Mehta, Swapnil, Du, Jinyan, Kazi, Julhash U, Luciano, Frédéric, Rönnstrand, Lars, Kung, Andrew L, Aster, Jon C, Galinsky, Ilene, Stone, Richard M, DeAngelo, Daniel J, Stegmaier, Kimberly, Fenouille, Nina, Hemann, Michael
Published 2017

Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma

by Chapuy, Bjoern, McKeown, Michael R, Lin, Charles Y, Monti, Stefano, Roemer, Margaretha G.M, Qi, Jun, Rahl, Peter B, Sun, Heather H, Yeda, Kelly T, Doench, John G, Reichert, Elaine, Kung, Andrew L, Rodig, Scott J, Young, Richard A, Shipp, Margaret A, Bradner, James E, Young, Richard A.
Published 2016

Targeting MTHFD2 in acute myeloid leukemia

by Pikman, Yana, Alexe, Gabriela, Furman, Andrew, Chen, Liying M., Frumm, Stacey M., Ross, Linda, Fenouille, Nina, Bassil, Christopher F., Gould, Joshua, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Clish, Clary B., Kung, Andrew L., Banerji, Versha, Stegmaier, Kimberly, Puissant, Alexandre, Lewis, Caroline, Ramos, Azucena, Hemann, Michael, Vander Heiden, Matthew G.
Published 2017

Targeting MTHFD2 in acute myeloid leukemia

by Pikman, Yana, Puissant, Alexandre, Alexe, Gabriela, Furman, Andrew, Chen, Liying M., Frumm, Stacey M., Ross, Linda, Fenouille, Nina, Bassil, Christopher F., Lewis, Caroline, Ramos, Azucena, Gould, Joshua, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Clish, Clary B., Kung, Andrew L., Hemann, Michael, Vander Heiden, Matthew G., Banerji, Versha, Stegmaier, Kimberly
Published 2022

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

by Delmore, Jake E, Issa, Ghayas C, Lemieux, Madeleine E., Rahl, Peter B, Shi, Junwei, Jacobs, Hannah M, Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M, Qi, Jun, Chesi, Marta, Schinzel, Anna C, McKeown, Michael R, Heffernan, Timothy P., Vakoc, Christopher R, Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G, Young, Richard A, Hahn, William C., Anderson, Kenneth C., Kung, Andrew L, Bradner, James E., Mitsiades, Constantine S.
Published 2014

STAG2 loss reshapes oncogenic enhancer-promoter looping in Ewing sarcoma

by Adane, Biniam, Alexe, Gabriela, Seong, Bo Kyung A., Lu, Diana, Hwang, Elizabeth E., Hnisz, Denes, Lareau, Caleb A., Ross, Linda, Lin, Shan, Dela Cruz, Filemon S., Richardson, Melissa, Weintraub, Abraham Selby, Wang, Sarah, Iniguez, Amanda Balboni, Dharia, Neekesh V., Conway, Amy Saur, Robichaud, Amanda L., Tanenbaum, Benjamin, Krill-Burger, John M., Vazquez, Francisca, Schenone, Monica, Berman, Jason N., Kung, Andrew L., Carr, Steven A., Aryee, Martin J., Young, Richard A., Crompton, Brian D., Stegmaier, Kimberly
Published 2021