Driving Circuitry for Focused Ultrasound Noninvasive Surgery and Drug Delivery Applications

by Kullervo Hynynen, Munir M. El-Desouki
Published 2011-01-01

Focused Ultrasound and Microbubbles-Mediated Drug Delivery to Brain Tumor

by Sheng-Kai Wu, Chia-Lin Tsai, Yuexi Huang, Kullervo Hynynen
Published 2021-12-01

Microbubble formulation influences inflammatory response to focused ultrasound exposure in the brain

by Dallan McMahon, Anne Lassus, Emmanuel Gaud, Victor Jeannot, Kullervo Hynynen
Published 2020-12-01

Focused Ultrasound-Induced Neurogenesis Requires an Increase in Blood-Brain Barrier Permeability.

by Skyler J Mooney, Kairavi Shah, Sharon Yeung, Alison Burgess, Isabelle Aubert, Kullervo Hynynen
Published 2016-01-01

High-intensity focused ultrasound (HIFU) for dissolution of clots in a rabbit model of embolic stroke.

by Alison Burgess, Yuexi Huang, Adam C Waspe, Milan Ganguly, David E Goertz, Kullervo Hynynen
Published 2012-01-01

Targeted delivery of neural stem cells to the brain using MRI-guided focused ultrasound to disrupt the blood-brain barrier.

by Alison Burgess, Carlos A Ayala-Grosso, Milan Ganguly, Jessica F Jordão, Isabelle Aubert, Kullervo Hynynen
Published 2011-01-01

A computerized tablet system for evaluating treatment of essential tremor by magnetic resonance guided focused ultrasound

by Fred Tam, Yuexi Huang, Michael L. Schwartz, Tom A. Schweizer, Kullervo Hynynen, Simon J. Graham
Published 2017-04-01

Antitumor effects of combining docetaxel (taxotere) with the antivascular action of ultrasound stimulated microbubbles.

by David E Goertz, Margarita Todorova, Omid Mortazavi, Vlad Agache, Branson Chen, Raffi Karshafian, Kullervo Hynynen
Published 2012-01-01

Stimulation of Hippocampal Neurogenesis by Transcranial Focused Ultrasound and Microbubbles in Adult Mice

by Tiffany Scarcelli, Jessica F. Jordão, Meaghan A. O'Reilly, Nicholas Ellens, Kullervo Hynynen, Isabelle Aubert
Published 2014-03-01

Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer's disease mouse models.

by Scott B Raymond, Lisa H Treat, Jonathan D Dewey, Nathan J McDannold, Kullervo Hynynen, Brian J Bacskai
Published 2008-05-01

Antibodies targeted to the brain with image-guided focused ultrasound reduces amyloid-beta plaque load in the TgCRND8 mouse model of Alzheimer's disease.

by Jessica F Jordão, Carlos A Ayala-Grosso, Kelly Markham, Yuexi Huang, Rajiv Chopra, JoAnne McLaurin, Kullervo Hynynen, Isabelle Aubert
Published 2010-05-01

Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery

by Danielle Weber-Adrian, Rikke Hahn Kofoed, Joseph Silburt, Zeinab Noroozian, Kairavi Shah, Alison Burgess, Shawna Rideout, Sebastian Kügler, Kullervo Hynynen, Isabelle Aubert
Published 2021-01-01

Abstract #14: Resting State Functional Connectivity Changes After MR-Guided Focused Ultrasound Mediated Blood-Brain Barrier Opening

by Ying Meng, Bradley J. MacIntosh, Zahra Shirzadi, Alex Kiss, Allison Bethune, Chris Heyn, Karim Mithani, Kullervo Hynynen, Sandra E. Black, Nir Lipsman
Published 2019-03-01

First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound

by Agessandro Abrahao, Ying Meng, Maheleth Llinas, Yuexi Huang, Clement Hamani, Todd Mainprize, Isabelle Aubert, Chinthaka Heyn, Sandra E. Black, Kullervo Hynynen, Nir Lipsman, Lorne Zinman
Published 2019-09-01

Systematic examination of low-intensity ultrasound parameters on human motor cortex excitability and behavior

by Anton Fomenko, Kai-Hsiang Stanley Chen, Jean-François Nankoo, James Saravanamuttu, Yanqiu Wang, Mazen El-Baba, Xue Xia, Shakthi Sanjana Seerala, Kullervo Hynynen, Andres M Lozano, Robert Chen
Published 2020-11-01

Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound

by Nir Lipsman, Ying Meng, Allison J. Bethune, Yuexi Huang, Benjamin Lam, Mario Masellis, Nathan Herrmann, Chinthaka Heyn, Isabelle Aubert, Alexandre Boutet, Gwenn S. Smith, Kullervo Hynynen, Sandra E. Black
Published 2018-07-01

The design and development of intracavitary ultrasound arrays for hyperthermia.

by Diederich, Chris John.
Published 1990

Cavitation methods in therapeutic ultrasound : techniques, mechanisms, and system design

by Sokka, Shunmugavelu D. (Shunmugavelu Doraivelu), 1975-
Published 2005

Design and evaluation of linear intracavitary ultrasound phased array for MRI-guided prostate ablative therapies

by Sokka, Shunmugavelu D. (Shunmugavelu Doraivelu), 1975-
Published 2013

A large scale phased array ultrasound system for non-invasive surgery of deep seated tissue

by Daum, Douglas R., 1968-
Published 2014