Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo.

by Kristina Preuße, Lena Tveriakhina, Karin Schuster-Gossler, Cláudia Gaspar, Alexandra Isabel Rosa, Domingos Henrique, Achim Gossler, Michael Stauber
Published 2015-06-01

Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestatio...

by Francis M Kobia, Kristina Preusse, Quanhui Dai, Nicholas Weaver, Matthew R Hass, Praneet Chaturvedi, Sarah J Stein, Warren S Pear, Zhenyu Yuan, Rhett A Kovall, Yi Kuang, Natanel Eafergen, David Sprinzak, Brian Gebelein, Eric W Brunskill, Raphael Kopan
Published 2020-10-01

Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism

by Yi Kuang, Ohad Golan, Kristina Preusse, Brittany Cain, Collin J Christensen, Joseph Salomone, Ian Campbell, FearGod V Okwubido-Williams, Matthew R Hass, Zhenyu Yuan, Nathanel Eafergan, Kenneth H Moberg, Rhett A Kovall, Raphael Kopan, David Sprinzak, Brian Gebelein
Published 2020-04-01