How to automatically turn patient experience free-text responses into actionable insights: a natural language programming (NLP) approach

by Simone A. Cammel, Marit S. De Vos, Daphne van Soest, Kristina M. Hettne, Fred Boer, Ewout W. Steyerberg, Hileen Boosman
Published 2020-05-01

Prioritization of novel ADPKD drug candidates from disease-stage specific gene expression profiles

by Tareq B. Malas, Wouter N. Leonhard, Hester Bange, Zoraide Granchi, Kristina M. Hettne, Gerard J.P. Van Westen, Leo S. Price, Peter A.C. 't Hoen, Dorien J.M. Peters
Published 2020-01-01

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

by Lodewijk J. A. Toonen, Maurice Overzier, Melvin M. Evers, Leticia G. Leon, Sander A. J. van der Zeeuw, Hailiang Mei, Szymon M. Kielbasa, Jelle J. Goeman, Kristina M. Hettne, Olafur Th. Magnusson, Marion Poirel, Alexandre Seyer, Peter A. C. ‘t Hoen, Willeke M. C. van Roon-Mom
Published 2018-06-01

The Implicitome: A Resource for Rationalizing Gene-Disease Associations.

by Kristina M Hettne, Mark Thompson, Herman H H B M van Haagen, Eelke van der Horst, Rajaram Kaliyaperumal, Eleni Mina, Zuotian Tatum, Jeroen F J Laros, Erik M van Mulligen, Martijn Schuemie, Emmelien Aten, Tong Shu Li, Richard Bruskiewich, Benjamin M Good, Andrew I Su, Jan A Kors, Johan den Dunnen, Gert-Jan B van Ommen, Marco Roos, Peter A C 't Hoen, Barend Mons, Erik A Schultes
Published 2016-01-01

Brain Transcriptomic Analysis of Hereditary Cerebral Hemorrhage With Amyloidosis-Dutch Type

by Laure Grand Moursel, Laure Grand Moursel, Willeke M. C. van Roon-Mom, Szymon M. Kiełbasa, Hailiang Mei, Henk P. J. Buermans, Linda M. van der Graaf, Linda M. van der Graaf, Kristina M. Hettne, Emile J. de Meijer, Sjoerd G. van Duinen, Jeroen F. J. Laros, Jeroen F. J. Laros, Mark A. van Buchem, Peter A. C. ‘t Hoen, Silvère M. van der Maarel, Louise van der Weerd, Louise van der Weerd
Published 2018-04-01