Specificity of Molecular Fragments Binding to S100B versus S100A1 as Identified by NMR and Site Identification by Ligand Competitive Saturation (SILCS)

by Brianna D. Young, Wenbo Yu, Darex J. Vera Rodríguez, Kristen M. Varney, Alexander D. MacKerell, David J. Weber
Published 2021-01-01

The Importance of Therapeutically Targeting the Binary Toxin from <i>Clostridioides difficile</i>

by Dinendra L. Abeyawardhane, Raquel Godoy-Ruiz, Kaylin A. Adipietro, Kristen M. Varney, Richard R. Rustandi, Edwin Pozharski, David J. Weber
Published 2021-03-01

Loss of S100A1 expression leads to Ca2+ release potentiation in mutant mice with disrupted CaM and S100A1 binding to CaMBD2 of RyR1

by Erick O. Hernández‐Ochoa, Zephan Melville, Camilo Vanegas, Kristen M. Varney, Paul T. Wilder, Werner Melzer, David J. Weber, Martin F. Schneider
Published 2018-08-01

Turning defense into offense: defensin mimetics as novel antibiotics targeting lipid II.

by Kristen M Varney, Alexandre M J J Bonvin, Marzena Pazgier, Jakob Malin, Wenbo Yu, Eugene Ateh, Taiji Oashi, Wuyuan Lu, Jing Huang, Marlies Diepeveen-de Buin, Joseph Bryant, Eefjan Breukink, Alexander D Mackerell, Erik P H de Leeuw
Published 2013-01-01

Development of a glycoconjugate vaccine to prevent invasive Salmonella Typhimurium infections in sub-Saharan Africa.

by Scott M Baliban, Mingjun Yang, Girish Ramachandran, Brittany Curtis, Surekha Shridhar, Rachel S Laufer, Jin Y Wang, John Van Druff, Ellen E Higginson, Nicolas Hegerle, Kristen M Varney, James E Galen, Sharon M Tennant, Andrew Lees, Alexander D MacKerell, Myron M Levine, Raphael Simon
Published 2017-04-01