Establishment of Chronic Typhoid Infection in a Mouse Carriage Model Involves a Type 2 Immune Shift and T and B Cell Recruitment to the Gallbladder

by Juan F. González, Jonathan Kurtz, David L. Bauer, Regan Hitt, James Fitch, Amy Wetzel, Krista La Perle, Peter White, James McLachlan, John S. Gunn
Published 2019-10-01

Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality.

by Arturo Orlacchio, Aaron E Stark, Claudia Foray, Foued Amari, Tyler Sheetz, Erika Reese, Anna Tessari, Krista La Perle, Dario Palmieri, Philip N Tsichlis, Vincenzo Coppola
Published 2018-01-01

Novel small molecule XPO1/CRM1 inhibitors induce nuclear accumulation of TP53, phosphorylated MAPK and apoptosis in human melanoma cells.

by Jennifer Yang, Matthew A Bill, Gregory S Young, Krista La Perle, Yosef Landesman, Sharon Shacham, Michael Kauffman, William Senapedis, Trinayan Kashyap, Jean-Richard Saint-Martin, Kari Kendra, Gregory B Lesinski
Published 2014-01-01

Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells

by Xiaohua Zhu, Mohamed Badawi, Steven Pomeroy, Dhruvitkumar S. Sutaria, Zhiliang Xie, Alice Baek, Jinmai Jiang, Ola A. Elgamal, Xiaokui Mo, Krista La Perle, Jeffrey Chalmers, Thomas D. Schmittgen, Mitch A. Phelps
Published 2017-12-01