Insulin Signaling and Insulin Resistance Facilitate Trained Immunity in Macrophages Through Metabolic and Epigenetic Changes

by Eleftheria Ieronymaki, Eleftheria Ieronymaki, Maria G. Daskalaki, Maria G. Daskalaki, Konstantina Lyroni, Konstantina Lyroni, Christos Tsatsanis, Christos Tsatsanis
Published 2019-06-01

Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis

by Maria C. Silva, Marcela Davoli-Ferreira, Tiago S. Medina, Renata Sesti-Costa, Grace K. Silva, Carla D. Lopes, Lucas E. Cardozo, Fábio N. Gava, Konstantina Lyroni, Fabrício C. Dias, Amanda F. Frade, Monique Baron, Helder I. Nakaya, Florêncio Figueiredo, José C. Alves-Filho, Fernando Q. Cunha, Christos Tsatsanis, Christophe Chevillard, Edecio Cunha-Neto, Emilio Hirsch, João S. Silva, Thiago M. Cunha
Published 2018-04-01