Transmembrane Activator and CAML Interactor (TACI): Another Potential Target for Immunotherapy of Multiple Myeloma?

by Shengli Xu, Kong-Peng Lam
Published 2020-04-01

Emerging Roles of Downstream of Kinase 3 in Cell Signaling

by Jia Tong Loh, Jia Tong Loh, Joey Kay Hui Teo, Joey Kay Hui Teo, Hong-Hwa Lim, Hong-Hwa Lim, Kong-Peng Lam, Kong-Peng Lam, Kong-Peng Lam, Kong-Peng Lam
Published 2020-09-01

ASK1 Mediates Nur77 Expression in T-Cell Receptor Mediated Thymocyte Apoptosis

by Jianxin Huo, Shengli Xu, Kong-Peng Lam
Published 2020-03-01

FAIM: An Antagonist of Fas-Killing and Beyond

by Jianxin Huo, Shengli Xu, Kong-Peng Lam
Published 2019-06-01

IL-10 Enhances Human Natural Killer Cell Effector Functions via Metabolic Reprogramming Regulated by mTORC1 Signaling

by Zixi Wang, Zixi Wang, Di Guan, Di Guan, Jianxin Huo, Jianxin Huo, Subhra K. Biswas, Yuhan Huang, Yuansheng Yang, Shengli Xu, Shengli Xu, Shengli Xu, Kong-Peng Lam, Kong-Peng Lam, Kong-Peng Lam
Published 2021-02-01

Bruton's tyrosine kinase and protein kinase C µ are required for TLR7/9-induced IKKα and IRF-1 activation and interferon-β production in conventional dendritic cells.

by Yan-Feng Li, Koon-Guan Lee, Xijun Ou, Kong-Peng Lam
Published 2014-01-01

Bruton’s tyrosine kinase regulates gut immune homeostasis through attenuating Th1 response

by Di Guan, Zixi Wang, Jianxin Huo, Shengli Xu, Kong-Peng Lam
Published 2021-04-01

Glycolysis and Oxidative Phosphorylation Play Critical Roles in Natural Killer Cell Receptor-Mediated Natural Killer Cell Functions

by Zixi Wang, Zixi Wang, Di Guan, Di Guan, Shu Wang, Louis Yi Ann Chai, Louis Yi Ann Chai, Shengli Xu, Shengli Xu, Kong-Peng Lam, Kong-Peng Lam
Published 2020-02-01

RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection.

by A M A Nasirudeen, Hui Hui Wong, Peiling Thien, Shengli Xu, Kong-Peng Lam, Ding Xiang Liu
Published 2011-01-01

Aberrant Presentation of Self-Lipids by Autoimmune B Cells Depletes Peripheral iNKT Cells

by Andy Hee-Meng Tan, William Pooi-Kat Chong, Sze-Wai Ng, Nurhidayah Basri, Shengli Xu, Kong-Peng Lam
Published 2014-10-01

Production of functional soluble Dectin-1 glycoprotein using an IRES-linked destabilized-dihydrofolate reductase expression vector.

by Say Kong Ng, Tessa Rui Min Tan, Yang Wang, Daniel Ng, Lin-Tang Goh, Muriel Bardor, Victor Vai Tak Wong, Kong Peng Lam
Published 2012-01-01

von Hippel-Lindau Protein Maintains Metabolic Balance to Regulate the Survival of Naive B Lymphocytes

by Shengli Xu, Jianxin Huo, Yuhan Huang, Melissa Aw, Shuwen Chen, Shiya Mak, Lian Yee Yip, Ying Swan Ho, Sze Wai Ng, Andy Hee-Meng Tan, Alison Lee, Xijun Ou, Kong-Peng Lam
Published 2019-07-01

Bruton’s Tyrosine Kinase Phosphorylates DDX41 and Activates Its Binding of dsDNA and STING to Initiate Type 1 Interferon Response

by Koon-Guan Lee, Susana Soo-Yeon Kim, Lin Kui, Dominic Chih-Cheng Voon, Marjorie Mauduit, Pradeep Bist, Xuezhi Bi, Natasha Ann Pereira, Chengcheng Liu, Bindu Sukumaran, Laurent Rénia, Yoshiaki Ito, Kong-Peng Lam
Published 2015-02-01

Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells

by Jia Tong Loh, Thomas Jun Feng Lim, Kyoko Ikumi, Takuma Matoba, Baptiste Janela, Merry Gunawan, Tatsuya Toyama, Maegan Bunjamin, Lai Guan Ng, Michael Poidinger, Akimichi Morita, Florent Ginhoux, Sayuri Yamazaki, Kong-Peng Lam, I-hsin Su
Published 2018-12-01

Basal immunoglobulin signaling actively maintains developmental stage in immature B cells.

by Lina E Tze, Brian R Schram, Kong-Peng Lam, Kristin A Hogquist, Keli L Hippen, Jiabin Liu, Susan A Shinton, Kevin L Otipoby, Peter R Rodine, Amanda L Vegoe, Manfred Kraus, Richard R Hardy, Mark S Schlissel, Klaus Rajewsky, Timothy W Behrens
Published 2005-03-01

TACI Constrains TH17 Pathogenicity and Protects against Gut Inflammation

by Andy Hee-Meng Tan, Gloria Hoi Wan Tso, Biyan Zhang, Pei-Yun Teo, Xijun Ou, Sze-Wai Ng, Alex Xing Fah Wong, Sean Jing Xiang Tan, Arleen Sanny, Susana Soo-Yeon Kim, Alison P. Lee, Shengli Xu, Kong-Peng Lam
Published 2020-11-01

Host-derived lipids orchestrate pulmonary γδ T cell response to provide early protection against influenza virus infection

by Xiaohui Wang, Xiang Lin, Zihan Zheng, Bingtai Lu, Jun Wang, Andy Hee-Meng Tan, Meng Zhao, Jia Tong Loh, Sze Wai Ng, Qian Chen, Fan Xiao, Enyu Huang, King-Hung Ko, Zhong Huang, Jingyi Li, Kin-Hang Kok, Gen Lu, Xiaohui Liu, Kong-Peng Lam, Wanli Liu, Yuxia Zhang, Kwok-Yung Yuen, Tak Wah Mak, Liwei Lu
Published 2021-03-01