Aged Gastroenterology Geriatrics Humans Inflammatory Bowel Diseases Liver Cirrhosis Review United States aged atropine plus diphenoxylate beta adrenergic receptor blocking agent chronic disease ciprofloxacin clinical practice corticosteroid diuretic agent evidence based practice gastroenterology geriatrics groups by age health care human hyoscyamine inflammatory bowel disease lactulose liver cirrhosis patient care process optimization tricyclic antidepressant agent vulnerable population