Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes

by Raja, Waseem K, Mungenast, Alison, Lin, Yuan-Ta, Ko, Tak, Abdurrob, Fatema, Seo, Jinsoo, Tsai, Li-Huei
Published 2017

Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior

by Zhang, Feiran, Jin, Peng, Nott, Alexander, Cheng, Jemmie, Gao, Fan, Lin, Yuan-Ta, Gjoneska, Elizabeta, Ko, Tak, Minhas, Paras S, Zamudio Montes de Oca, Alicia, Meng, Jia, Tsai, Li-Huei
Published 2017

Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia

by Silva, M. Catarina, Sheridan, Steven D., Lucente, Diane, Gusella, James F., Dickerson, Bradford C., Haggarty, Stephen J., Tsai, Li-Huei, Seo, Jinsoo, Kritskiy, Oleg, Watson, Lauren Ashley, Barker, Scarlett Jazmine, Dey, Dilip Chandra, Raja, Waseem K, Lin, Yuan-Ta, Ko, Tak, Cho, Sukhee, Penney, Jay
Published 2018

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types

by Lin, Yuan-Ta, Seo, Jinsoo, Gao, Fan, Feldman, Heather M., Wen, Hsin-Lan, Penney, Jay, Cam, Hugh P., Gjoneska, Elizabeta, Raja, Waseem K, Cheng, Jemmie, Rueda IV, Richard, Kritskiy, Oleg, Abdurrob, Fatema, Peng, Zhuyu, Milo, Blerta, Yu, Chung Jong, Elmsaouri, Sara, Dey, Dilip Chandra, Ko, Tak, Yankner, Bruce A., Tsai, Li-Huei
Published 2020

Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds

by Dele-Oni, Deborah O, Christianson, Karen E, Egri, Shawn B, Vaca Jacome, Alvaro Sebastian, DeRuff, Katherine C, Mullahoo, James, Sharma, Vagisha, Davison, Desiree, Ko, Tak, Bula, Michael, Blanchard, Joel, Young, Jennie Z, Litichevskiy, Lev, Lu, Xiaodong, Lam, Daniel, Asiedu, Jacob K, Toder, Caidin, Officer, Adam, Peckner, Ryan, MacCoss, Michael J, Tsai, Li-Huei, Carr, Steven A, Papanastasiou, Malvina, Jaffe, Jacob D
Published 2021

Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds

by Dele-Oni, Deborah O., Christianson, Karen E., Egri, Shawn B., Vaca Jacome, Alvaro Sebastian, DeRuff, Katherine C., Mullahoo, James, Sharma, Vagisha, Davison, Desiree, Ko, Tak, Bula, Michael, Blanchard, Joel, Young, Jennie Z., Litichevskiy, Lev, Lu, Xiaodong, Lam, Daniel, Asiedu, Jacob K., Toder, Caidin, Officer, Adam, Peckner, Ryan, MacCoss, Michael J., Tsai, Li-Huei, Carr, Steven A., Papanastasiou, Malvina, Jaffe, Jacob D.
Published 2022

A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations

by Litichevskiy, Lev, Peckner, Ryan, Abelin, Jennifer G., Asiedu, Jacob K., Creech, Amanda L., Davis, John F., Davison, Desiree, Dunning, Caitlin M., Egertson, Jarrett D., Egri, Shawn, Gould, Joshua, Ko, Tak, Johnson, Sarah A., Lahr, David L., Lam, Daniel, Liu, Zihan, MacLean, Brendan X., Lyons, Nicholas J., Lu, Xiaodong, Mungenast, Alison, Officer, Adam, Natoli, Ted E., Papanastasiou, Malvina, Patel, Jinal, Sharma, Vagisha, Toder, Courtney, Tubelli, Andrew A., Young, Jennie Zin-Ney, Carr, Steven A, Golub, Todd, Subramanian, Aravind, MacCoss, Michael J., Tsai, Li-Huei, Jaffe, Jacob D
Published 2020