LXR Inhibits Proliferation of Human Breast Cancer Cells through the PI3K-Akt Pathway

by Treska S. Hassan, Aida Paniccia, Vincenzo Russo, Knut R. Steffensen
Published 2015-05-01

Liver X receptor regulation of thyrotropin-releasing hormone transcription in mouse hypothalamus is dependent on thyroid status.

by Rym Ghaddab-Zroud, Isabelle Seugnet, Knut R Steffensen, Barbara A Demeneix, Marie-Stéphanie Clerget-Froidevaux
Published 2014-01-01

Anti-inflammatory nuclear receptor superfamily in multiple sclerosis patients from Sardinia and Sweden

by Xuan Liu, Knut R. Steffensen, Alessandra Sanna, Giannina Arru, Maria Laura Fois, Giulio Rosati, Stefano Sotgiu, Hans Link, Jan-Åke Gustafsson, Yu-Min Huang
Published 2005-12-01

Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.

by Karine H Hellemans, Jean-Claude Hannaert, Bart Denys, Knut R Steffensen, Cindy Raemdonck, Geert A Martens, Paul P Van Veldhoven, Jan-Ake Gustafsson, Daniel Pipeleers
Published 2009-09-01

Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice.

by Matteo Pedrelli, Padideh Davoodpour, Chiara Degirolamo, Monica Gomaraschi, Mark Graham, Alice Ossoli, Lilian Larsson, Laura Calabresi, Jan-Åke Gustafsson, Knut R Steffensen, Mats Eriksson, Paolo Parini
Published 2014-01-01

Srebf1 Controls Midbrain Dopaminergic Neurogenesis

by Enrique M. Toledo, Shanzheng Yang, Daniel Gyllborg, Kim E. van Wijk, Indranil Sinha, Manuel Varas-Godoy, Christopher L. Grigsby, Peter Lönnerberg, Saiful Islam, Knut R. Steffensen, Sten Linnarsson, Ernest Arenas
Published 2020-05-01

Myelin-derived lipids modulate macrophage activity by liver X receptor activation.

by Jeroen F J Bogie, Silke Timmermans, Vân Anh Huynh-Thu, Alexandre Irrthum, Hubert J M Smeets, Jan-Åke Gustafsson, Knut R Steffensen, Monique Mulder, Piet Stinissen, Niels Hellings, Jerome J A Hendriks
Published 2012-01-01

Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity[S]

by Christian Bindesbøll, Qiong Fan, Rikke C. Nørgaard, Laura MacPherson, Hai-Bin Ruan, Jing Wu, Thomas Å. Pedersen, Knut R. Steffensen, Xiaoyong Yang, Jason Matthews, Susanne Mandrup, Hilde I. Nebb, Line M. Grønning-Wang
Published 2015-04-01

Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors

by Raffaella Fontana, Laura Raccosta, Lucrezia Rovati, Knut R. Steffensen, Aida Paniccia, Tomas Jakobsson, Giulio Melloni, Alessandro Bandiera, Giorgia Mangili, Alice Bergamini, Daniela Maggioni, Claudio Doglioni, Roberto Crocchiolo, Marina Cella, Michela Mattioli, Cristina Battaglia, Marco Colonna, Vincenzo Russo
Published 2019-03-01

Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function

by Elien Wouters, Nienke M. de Wit, Jasmine Vanmol, Susanne M. A. van der Pol, Bert van het Hof, Daniela Sommer, Melanie Loix, Dirk Geerts, Jan Ake Gustafsson, Jan Ake Gustafsson, Knut R. Steffensen, Tim Vanmierlo, Tim Vanmierlo, Jeroen F. J. Bogie, Jerome J. A. Hendriks, Helga E. de Vries
Published 2019-07-01

Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells.

by Nicholes R Candelaria, Sridevi Addanki, Jine Zheng, Trang Nguyen-Vu, Husna Karaboga, Prasenjit Dey, Chiara Gabbi, Lise-Lotte Vedin, Ka Liu, Wanfu Wu, Philip K Jonsson, Jean Z Lin, Fei Su, Lakshmi Reddy Bollu, Sally E Hodges, Amy L McElhany, Mehdi A Issazadeh, William E Fisher, Michael M Ittmann, Knut R Steffensen, Jan-Åke Gustafsson, Chin-Yo Lin
Published 2014-01-01