Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron(II) and 2-oxoglutarate-dependent dioxygenase EctD.

by Klaus Reuter, Marco Pittelkow, Jan Bursy, Andreas Heine, Tobias Craan, Erhard Bremer
Published 2010-05-01

Soaking suggests "alternative facts": Only co-crystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-...

by Frederik Rainer Ehrmann, Johann Stojko, Alexander Metz, François Debaene, Luzi Jakob Barandun, Andreas Heine, François Diederich, Sarah Cianférani, Klaus Reuter, Gerhard Klebe
Published 2017-01-01

Investigation of specificity determinants in bacterial tRNA-guanine transglycosylase reveals queuine, the substrate of its eucaryotic counterpart, as inhibitor.

by Inna Biela, Naomi Tidten-Luksch, Florian Immekus, Serghei Glinca, Tran Xuan Phong Nguyen, Hans-Dieter Gerber, Andreas Heine, Gerhard Klebe, Klaus Reuter
Published 2013-01-01