Anticancer effects of 15d-prostaglandin-J2 in wild-type and doxorubicin-resistant ovarian cancer cells: novel actions on SIRT1 and HDAC.

by Edwin de Jong, Peter Winkel, Klaas Poelstra, Jai Prakash
Published 2011-01-01

Targeted recombinant fusion proteins of IFNγ and mimetic IFNγ with PDGFβR bicyclic peptide inhibits liver fibrogenesis in vivo.

by Ruchi Bansal, Jai Prakash, Marieke De Ruiter, Klaas Poelstra
Published 2014-01-01

Enhanced effectivity of an ALK5-inhibitor after cell-specific delivery to hepatic stellate cells in mice with liver injury.

by Marike Marjolijn van Beuge, Jai Prakash, Marie Lacombe, Eduard Post, Catharina Reker-Smit, Leonie Beljaars, Klaas Poelstra
Published 2013-01-01

Precision-cut kidney slices (PCKS) to study development of renal fibrosis and efficacy of drug targeting ex vivo

by Fariba Poosti, Bao Tung Pham, Dorenda Oosterhuis, Klaas Poelstra, Harry van Goor, Peter Olinga, Jan-Luuk Hillebrands
Published 2015-10-01

Albumin-Binding and Tumor Vasculature Determine the Antitumor Effect of 15-Deoxy-Δ12,14-Prostaglandin-J2in vivo

by Jai Prakash, Ruchi Bansal, Eduard Post, Alie de Jager-Krikken, Marjolijn N. Lub-de Hooge, Klaas Poelstra
Published 2009-12-01

Design of a Gene Panel to Expose the Versatile Role of Hepatic Stellate Cells in Human Liver Fibrosis

by Fransien van Dijk, Christa M. Hazelhoff, Eduard Post, Gerian G. H. Prins, Krista Rombouts, Klaas Poelstra, Peter Olinga, Leonie Beljaars
Published 2020-03-01

Phosphate Groups in the Lipid A Moiety Determine the Effects of LPS on Hepatic Stellate Cells: A Role for LPS-Dephosphorylating Activity in Liver Fibrosis

by Marlies Schippers, Eduard Post, Ilse Eichhorn, Jitske Langeland, Leonie Beljaars, Madhu S. Malo, Richard A. Hodin, José Luis Millán, Yury Popov, Detlef Schuppan, Klaas Poelstra
Published 2020-12-01

Osteoprotegerin is More than a Possible Serum Marker in Liver Fibrosis: A Study into its Function in Human and Murine Liver

by Adhyatmika Adhyatmika, Leonie Beljaars, Kurnia S. S. Putri, Habibie Habibie, Carian E. Boorsma, Catharina Reker-Smit, Theerut Luangmonkong, Burak Guney, Axel Haak, Keri A. Mangnus, Eduard Post, Klaas Poelstra, Kim Adhyatmika, Peter Olinga, Barbro N. Melgert
Published 2020-05-01