Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health

by Riikka Jokinen, Sini Pirnes-Karhu, Kirsi H. Pietiläinen, Eija Pirinen
Published 2017-08-01

Transglutaminases and Obesity in Humans: Association of <i>F13A1</i> to Adipocyte Hypertrophy and Adipose Tissue Immune Response

by Mari T. Kaartinen, Mansi Arora, Sini Heinonen, Aila Rissanen, Jaakko Kaprio, Kirsi H. Pietiläinen
Published 2020-11-01

Modified Atkins diet modifies cardiopulmonary exercise characteristics and promotes hyperventilation in healthy subjects

by Nadja Ratia, Kirsi H. Pietiläinen, Mari Auranen, Lauri Saksa, Ritva Luukkonen, Anu Suomalainen, Päivi Piirilä
Published 2021-06-01

Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects--a monozygotic twin study.

by Kirsi H Pietiläinen, Marko Sysi-Aho, Aila Rissanen, Tuulikki Seppänen-Laakso, Hannele Yki-Järvinen, Jaakko Kaprio, Matej Oresic
Published 2007-02-01

Influence of serotonin transporter gene polymorphism (5-HTTLPR polymorphism) on the relation between brain 5-HT transporter binding and heart rate corrected cardiac repolarization...

by Esa Kauppila, Esko Vanninen, Salla Kaurijoki, Leila Karhunen, Kirsi H Pietiläinen, Aila Rissanen, Jari Tiihonen, Ullamari Pesonen, Jaakko Kaprio
Published 2013-01-01

Evaluation of the effect of donor weight on adipose stromal/stem cell characteristics by using weight-discordant monozygotic twin pairs

by Miia Juntunen, Sini Heinonen, Heini Huhtala, Aila Rissanen, Jaakko Kaprio, Kirsi Kuismanen, Kirsi H. Pietiläinen, Susanna Miettinen, Mimmi Patrikoski
Published 2021-09-01

An integrative machine learning approach to discovering multi-level molecular mechanisms of obesity using data from monozygotic twin pairs

by Milla Kibble, Suleiman A. Khan, Muhammad Ammad-ud-din, Sailalitha Bollepalli, Teemu Palviainen, Jaakko Kaprio, Kirsi H. Pietiläinen, Miina Ollikainen
Published 2020-10-01

Development of a Food-Based Diet Quality Score from a Short FFQ and Associations with Obesity Measures, Eating Styles and Nutrient Intakes in Finnish Twins

by Guiomar Masip, Anna Keski-Rahkonen, Kirsi H. Pietiläinen, Urho M. Kujala, Mirva Rottensteiner, Karoliina Väisänen, Jaakko Kaprio, Leonie H. Bogl
Published 2019-10-01

Accurate estimation of cell composition in bulk expression through robust integration of single-cell information

by Brandon Jew, Marcus Alvarez, Elior Rahmani, Zong Miao, Arthur Ko, Kristina M. Garske, Jae Hoon Sul, Kirsi H. Pietiläinen, Päivi Pajukanta, Eran Halperin
Published 2020-04-01

Serum angiopoietin-like 4 protein levels and expression in adipose tissue are inversely correlated with obesity in monozygotic twins

by Marius R. Robciuc, Jussi Naukkarinen, Alfredo Ortega-Alonso, Henna Tyynismaa, Taneli Raivio, Aila Rissanen, Jaakko Kaprio, Christian Ehnholm, Matti Jauhiainen, Kirsi H. Pietiläinen
Published 2011-08-01

Publisher Correction: Accurate estimation of cell composition in bulk expression through robust integration of single-cell information

by Brandon Jew, Marcus Alvarez, Elior Rahmani, Zong Miao, Arthur Ko, Kristina M. Garske, Jae Hoon Sul, Kirsi H. Pietiläinen, Päivi Pajukanta, Eran Halperin
Published 2020-06-01

Upregulation of Early and Downregulation of Terminal Pathway Complement Genes in Subcutaneous Adipose Tissue and Adipocytes in Acquired Obesity

by Sanna Kaye, Sanna Kaye, A. Inkeri Lokki, A. Inkeri Lokki, A. Inkeri Lokki, Anna Hanttu, Eija Nissilä, Eija Nissilä, Sini Heinonen, Antti Hakkarainen, Jesper Lundbom, Nina Lundbom, Lilli Saarinen, Olli Tynninen, Maheswary Muniandy, Maheswary Muniandy, Aila Rissanen, Aila Rissanen, Jaakko Kaprio, Jaakko Kaprio, Seppo Meri, Seppo Meri, Kirsi H. Pietiläinen, Kirsi H. Pietiläinen
Published 2017-05-01

Metabolomes of mitochondrial diseases and inclusion body myositis patients: treatment targets and biomarkers

by Jana Buzkova, Joni Nikkanen, Sofia Ahola, Anna H Hakonen, Ksenia Sevastianova, Topi Hovinen, Hannele Yki‐Järvinen, Kirsi H Pietiläinen, Tuula Lönnqvist, Vidya Velagapudi, Christopher J Carroll, Anu Suomalainen
Published 2018-12-01

Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity.

by Kirsi H Pietiläinen, Jussi Naukkarinen, Aila Rissanen, Juha Saharinen, Pekka Ellonen, Heli Keränen, Anu Suomalainen, Alexandra Götz, Tapani Suortti, Hannele Yki-Järvinen, Matej Oresic, Jaakko Kaprio, Leena Peltonen
Published 2008-03-01

Regional fat depot masses are influenced by protein-coding gene variants.

by Matt J Neville, Laura B L Wittemans, Katherine E Pinnick, Marijana Todorčević, Risto Kaksonen, Kirsi H Pietiläinen, Jian'an Luan, Robert A Scott, Nicholas J Wareham, Claudia Langenberg, Fredrik Karpe
Published 2019-01-01

Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.

by Jussi Naukkarinen, Ida Surakka, Kirsi H Pietiläinen, Aila Rissanen, Veikko Salomaa, Samuli Ripatti, Hannele Yki-Järvinen, Cornelia M van Duijn, H-Erich Wichmann, Jaakko Kaprio, Marja-Riitta Taskinen, Leena Peltonen, ENGAGE Consortium
Published 2010-06-01

The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance.

by Zong Miao, Marcus Alvarez, Arthur Ko, Yash Bhagat, Elior Rahmani, Brandon Jew, Sini Heinonen, Linda Liliana Muñoz-Hernandez, Miguel Herrera-Hernandez, Carlos Aguilar-Salinas, Teresa Tusie-Luna, Karen L Mohlke, Markku Laakso, Kirsi H Pietiläinen, Eran Halperin, Päivi Pajukanta
Published 2020-09-01

Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men.

by Niina Matikainen, Elias Björnson, Sanni Söderlund, Christofer Borén, Björn Eliasson, Kirsi H Pietiläinen, Leonie H Bogl, Antti Hakkarainen, Nina Lundbom, Angela Rivellese, Gabriele Riccardi, Jean-Pierre Després, Natalie Alméras, Jens Juul Holst, Carolyn F Deacon, Jan Borén, Marja-Riitta Taskinen
Published 2016-01-01

Systemic cross-talk between brain, gut, and peripheral tissues in glucose homeostasis: effects of exercise training (CROSSYS). Exercise training intervention in monozygotic twins d...

by Marja A. Heiskanen, Sanna M. Honkala, Jaakko Hentilä, Ronja Ojala, Riikka Lautamäki, Kalle Koskensalo, Martin S. Lietzén, Virva Saunavaara, Jani Saunavaara, Mika Helmiö, Eliisa Löyttyniemi, Lauri Nummenmaa, Maria C. Collado, Tarja Malm, Leo Lahti, Kirsi H. Pietiläinen, Jaakko Kaprio, Juha O. Rinne, Jarna C. Hannukainen
Published 2021-02-01

Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

by David Z. Pan, Zong Miao, Caroline Comenho, Sandhya Rajkumar, Amogha Koka, Seung Hyuk T. Lee, Marcus Alvarez, Dorota Kaminska, Arthur Ko, Janet S. Sinsheimer, Karen L. Mohlke, Nicholas Mancuso, Linda Liliana Muñoz-Hernandez, Miguel Herrera-Hernandez, Maria Teresa Tusié-Luna, Carlos Aguilar-Salinas, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Markku Laakso, Kristina M. Garske, Päivi Pajukanta
Published 2021-08-01