Immunotherapy Goes Local: The Central Role of Lymph Nodes in Driving Tumor Infiltration and Efficacy

by Kim M. van Pul, Marieke F. Fransen, Rieneke van de Ven, Tanja D. de Gruijl
Published 2021-03-01

Breast cancer-induced immune suppression in the sentinel lymph node is effectively countered by CpG-B in conjunction with inhibition of the JAK2/STAT3 pathway

by Kim M van Pul, Ronald J C L M Vuylsteke, Monique T A de Beijer, Hein B A C Stockmann
Published 2020-07-01

Selectively hampered activation of lymph node-resident dendritic cells precedes profound T cell suppression and metastatic spread in the breast cancer sentinel lymph node

by Kim M. van Pul, Ronald J.C.L.M. Vuylsteke, Rieneke van de Ven, Elisabeth A. te Velde, Emiel J. Th. Rutgers, Petrousjka M. van den Tol, Hein B.A.C. Stockmann, Tanja D. de Gruijl
Published 2019-05-01