Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs

by Madhusudhan Srinivasan, Marco Fumasoni, Naomi J Petela, Andrew Murray, Kim A Nasmyth
Published 2020-06-01

Cohesin Can Remain Associated with Chromosomes during DNA Replication

by James D.P. Rhodes, Judith H.I. Haarhuis, Jonathan B. Grimm, Benjamin D. Rowland, Luke D. Lavis, Kim A. Nasmyth
Published 2017-09-01

Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1

by Madhusudhan Srinivasan, Naomi J Petela, Johanna C Scheinost, James Collier, Menelaos Voulgaris, Maurici B Roig, Frederic Beckouët, Bin Hu, Kim A Nasmyth
Published 2019-06-01

Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3

by James E Collier, Byung-Gil Lee, Maurici Brunet Roig, Stanislav Yatskevich, Naomi J Petela, Jean Metson, Menelaos Voulgaris, Andres Gonzalez Llamazares, Jan Löwe, Kim A Nasmyth
Published 2020-09-01

Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes

by Naomi J Petela, Andres Gonzalez Llamazares, Sarah Dixon, Bin Hu, Byung-Gil Lee, Jean Metson, Heekyo Seo, Antonio Ferrer-Harding, Menelaos Voulgaris, Thomas Gligoris, James Collier, Byung-Ha Oh, Jan Löwe, Kim A Nasmyth
Published 2021-07-01

Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells

by James D.P. Rhodes, Angelika Feldmann, Benjamín Hernández-Rodríguez, Noelia Díaz, Jill M. Brown, Nadezda A. Fursova, Neil P. Blackledge, Praveen Prathapan, Paula Dobrinic, Miles K. Huseyin, Aleksander Szczurek, Kai Kruse, Kim A. Nasmyth, Veronica J. Buckle, Juan M. Vaquerizas, Robert J. Klose
Published 2020-01-01