Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome.

by Murthy Narayana Darisipudi, Ramanjaneyulu Allam, Khader Valli Rupanagudi, Hans-Joachim Anders
Published 2011-01-01

Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.

by Julia Lichtnekert, Onkar P Kulkarni, Shrikant R Mulay, Khader Valli Rupanagudi, Mi Ryu, Ramanjaneyulu Allam, Volker Vielhauer, Dan Muruve, Maja T Lindenmeyer, Clemens D Cohen, Hans-Joachim Anders
Published 2011-01-01