Targeting Adenosine Receptor Signaling in Cancer Immunotherapy

by Kevin Sek, Christina Mølck, Gregory D. Stewart, Lev Kats, Phillip K. Darcy, Paul A. Beavis
Published 2018-12-01

126 Early-phenotype Lewis Y CAR-T cells persist better in vivo and induce solid tumor regression in combination with anti-PD1

by Deborah Meyran, Joe Zhu, Jeanne Butler, Sean Macdonald, Daniela Tantalo, Niko Thio, Kevin Sek, Paul Ekert, Michael Kershaw, Joe Trapani, Phillip Darcy, Paul Neeson
Published 2020-11-01

CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy

by Lauren Giuffrida, Kevin Sek, Melissa A. Henderson, Junyun Lai, Amanda X. Y. Chen, Deborah Meyran, Kirsten L. Todd, Emma V. Petley, Sherly Mardiana, Christina Mølck, Gregory D. Stewart, Benjamin J. Solomon, Ian A. Parish, Paul J. Neeson, Simon J. Harrison, Lev M. Kats, Imran G. House, Phillip K. Darcy, Paul A. Beavis
Published 2021-05-01

MAIT cells regulate NK cell-mediated tumor immunity

by Emma V. Petley, Hui-Fern Koay, Melissa A. Henderson, Kevin Sek, Kirsten L. Todd, Simon P. Keam, Junyun Lai, Imran G. House, Jasmine Li, Magnus Zethoven, Amanda X. Y. Chen, Amanda J. Oliver, Jessica Michie, Andrew J. Freeman, Lauren Giuffrida, Jack D. Chan, Angela Pizzolla, Jeffrey Y. W. Mak, Timothy R. McCulloch, Fernando Souza-Fonseca-Guimaraes, Conor J. Kearney, Rosemary Millen, Robert G. Ramsay, Nicholas D. Huntington, James McCluskey, Jane Oliaro, David P. Fairlie, Paul J. Neeson, Dale I. Godfrey, Paul A. Beavis, Phillip K. Darcy
Published 2021-08-01