Ack1: activation and regulation by allostery.

by Ketan S Gajiwala, Karen Maegley, RoseAnn Ferre, You-Ai He, Xiu Yu
Published 2013-01-01

Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers.

by Luping Qiu, Kymberly Levine, Ketan S Gajiwala, Ciarán N Cronin, Asako Nagata, Eric Johnson, Michelle Kraus, John Tatlock, Robert Kania, Timothy Foley, Shaoxian Sun
Published 2018-01-01

Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2

by Yicheng Long, Ben Bolanos, Lihu Gong, Wei Liu, Karen J Goodrich, Xin Yang, Siming Chen, Anne R Gooding, Karen A Maegley, Ketan S Gajiwala, Alexei Brooun, Thomas R Cech, Xin Liu
Published 2017-11-01

Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance

by Alexei Brooun, Ketan S. Gajiwala, Ya-Li Deng, Wei Liu, Ben Bolaños, Patrick Bingham, You-Ai He, Wade Diehl, Nicole Grable, Pei-Pei Kung, Scott Sutton, Karen A. Maegley, Xiu Yu, Al E. Stewart
Published 2016-04-01