Calpain-Mediated Processing of Adenylate Cyclase Toxin Generates a Cytosolic Soluble Catalytically Active N-Terminal Domain.

by Kepa B Uribe, Aitor Etxebarria, César Martín, Helena Ostolaza
Published 2013-01-01

Adenylate cyclase toxin promotes internalisation of integrins and raft components and decreases macrophage adhesion capacity.

by César Martín, Kepa B Uribe, Geraxane Gómez-Bilbao, Helena Ostolaza
Published 2011-01-01

Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes

by Helena Ostolaza, César Martín, David González-Bullón, Kepa B. Uribe, Asier Etxaniz
Published 2017-09-01

Ca2+ influx and tyrosine kinases trigger Bordetella adenylate cyclase toxin (ACT) endocytosis. Cell physiology and expression of the CD11b/CD18 integrin major determinants of the e...

by Kepa B Uribe, César Martín, Aitor Etxebarria, David González-Bullón, Geraxane Gómez-Bilbao, Helena Ostolaza
Published 2013-01-01

Familial Hypercholesterolemia: The Most Frequent Cholesterol Metabolism Disorder Caused Disease

by Asier Benito-Vicente, Kepa B. Uribe, Shifa Jebari, Unai Galicia-Garcia, Helena Ostolaza, Cesar Martin
Published 2018-11-01

Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form?

by Helena Ostolaza, David González-Bullón, Kepa B. Uribe, Cesar Martín, Jone Amuategi, Xabier Fernandez-Martínez
Published 2019-06-01

Validation of LDLr Activity as a Tool to Improve Genetic Diagnosis of Familial Hypercholesterolemia: A Retrospective on Functional Characterization of LDLr Variants

by Asier Benito-Vicente, Kepa B. Uribe, Shifa Jebari, Unai Galicia-Garcia, Helena Ostolaza, Cesar Martin
Published 2018-06-01

Membrane Permeabilization by <i>Bordetella</i> Adenylate Cyclase Toxin Involves Pores of Tunable Size

by David González-Bullón, Kepa B. Uribe, Eneko Largo, Garazi Guembelzu, Aritz B. García-Arribas, César Martín, Helena Ostolaza
Published 2019-05-01

Pathophysiology of Type 2 Diabetes Mellitus

by Unai Galicia-Garcia, Asier Benito-Vicente, Shifa Jebari, Asier Larrea-Sebal, Haziq Siddiqi, Kepa B. Uribe, Helena Ostolaza, César Martín
Published 2020-08-01

Statin Treatment-Induced Development of Type 2 Diabetes: From Clinical Evidence to Mechanistic Insights

by Unai Galicia-Garcia, Shifa Jebari, Asier Larrea-Sebal, Kepa B. Uribe, Haziq Siddiqi, Helena Ostolaza, Asier Benito-Vicente, César Martín
Published 2020-07-01

Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid Composition

by Shifa Jebari-Benslaiman, Kepa B. Uribe, Asier Benito-Vicente, Unai Galicia-Garcia, Asier Larrea-Sebal, Iraide Alloza, Koen Vandenbroeck, Helena Ostolaza, César Martín
Published 2020-09-01

miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression

by Asier Benito-Vicente, Kepa B. Uribe, Noemi Rotllan, Cristina M. Ramírez, Shifa Jebari-Benslaiman, Leigh Goedeke, Alberto Canfrán-Duque, Unai Galicia-García, Diego Saenz De Urturi, Patricia Aspichueta, Yajaira Suárez, Carlos Fernández-Hernando, Cesar Martín
Published 2020-11-01