PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance

by Maddison Rose, Joshua T. Burgess, Kenneth O’Byrne, Kenneth O’Byrne, Derek J. Richard, Emma Bolderson
Published 2020-09-01

Cell Metabolism and DNA Repair Pathways: Implications for Cancer Therapy

by Thais Sobanski, Maddison Rose, Amila Suraweera, Kenneth O’Byrne, Kenneth O’Byrne, Derek J. Richard, Emma Bolderson, Emma Bolderson
Published 2021-03-01

The Prognostic Role of Circulating Tumor Cells (CTCs) in Lung Cancer

by Joanna Kapeleris, Joanna Kapeleris, Arutha Kulasinghe, Arutha Kulasinghe, Majid E. Warkiani, Majid E. Warkiani, Ian Vela, Ian Vela, Liz Kenny, Kenneth O'Byrne, Kenneth O'Byrne, Kenneth O'Byrne, Chamindie Punyadeera, Chamindie Punyadeera
Published 2018-08-01

43 Highly multiplexed digital spatial profiling of the tumor microenvironment of non-small-cell lung cancer (NSCLC)

by Arutha Kulasinghe, Connor O’Leary, Rahul Ladwa, Majid Warkiani, Kenneth O’byrne
Published 2020-11-01

Phenotypic Characterization of Circulating Lung Cancer Cells for Clinically Actionable Targets

by Arutha Kulasinghe, Joanna Kapeleris, Carolina Cooper, Majid Ebrahimi Warkiani, Kenneth O’Byrne, Chamindie Punyadeera
Published 2019-03-01

Correction: Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung ca...

by Magdalena Circu, James Cardelli, Martin P Barr, Kenneth O'Byrne, Glenn Mills, Hazem El-Osta
Published 2018-01-01

Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung cancer cells.

by Magdalena Circu, James Cardelli, Martin P Barr, Kenneth O'Byrne, Glenn Mills, Hazem El-Osta
Published 2017-01-01

Identification and clinical impact of potentially actionable somatic oncogenic mutations in solid tumor samples

by Sinead Toomey, Aoife Carr, Mateusz Janusz Mezynski, Yasir Elamin, Shereen Rafee, Mattia Cremona, Clare Morgan, Stephen Madden, Khairun I. Abdul-Jalil, Kathy Gately, Angela Farrelly, Elaine W. Kay, Susan Kennedy, Kenneth O’Byrne, Liam Grogan, Oscar Breathnach, Patrick G. Morris, Alexander J. Eustace, Joanna Fay, Robert Cummins, Anthony O’Grady, Roshni Kalachand, Norma O’Donovan, Fergal Kelleher, Aine O’Reilly, Mark Doherty, John Crown, Bryan T. Hennessy
Published 2020-02-01