Distinct functional consequences of ECEL1/DINE missense mutations in the pathogenesis of congenital contracture disorders

by Kenichi Nagata, Mika Takahashi, Sumiko Kiryu-Seo, Hiroshi Kiyama, Takaomi C. Saido
Published 2017-11-01

Generation of App knock-in mice reveals deletion mutations protective against Alzheimer’s disease-like pathology

by Kenichi Nagata, Mika Takahashi, Yukio Matsuba, Fumi Okuyama-Uchimura, Kaori Sato, Shoko Hashimoto, Takashi Saito, Takaomi C. Saido
Published 2018-05-01

Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID

by Hiroki Sasaguri, Kenichi Nagata, Misaki Sekiguchi, Ryo Fujioka, Yukio Matsuba, Shoko Hashimoto, Kaori Sato, Deepika Kurup, Takanori Yokota, Takaomi C. Saido
Published 2018-07-01