A state-of-the-art perspective on microgliopathic pain

by Kazuhide Inoue
Published 2018-11-01

ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Chronic Pain and Microglia: Involvement of the ATP Receptor P2X4

by Kazuhide Inoue, Makoto Tsuda, Schuichi Koizumi
Published 2004-01-01

Microglial Regulation of Neuropathic Pain

by Makoto Tsuda, Takahiro Masuda, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue
Published 2013-01-01

Selective Up-regulation of P2X4-Receptor Gene Expression by Interferon-γ in Vascular Endothelial Cells

by Yan Tang, Isao Matsuoka, Tomoyuki Ono, Kazuhide Inoue, Junko Kimura
Published 2008-01-01

ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Synaptic Purinoceptors: the Stage for ATP to Play Its “Dual-Role”

by Fusao Kato, Masahito Kawamura, Eiji Shigetomi, Jun-ichi Tanaka, Kazuhide Inoue
Published 2004-01-01

Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation

by Tomofumi Fujino, Mizuho Une, Tsuneo Imanaka, Kazuhide Inoue, Tomoko Nishimaki-Mogami
Published 2004-01-01

Direct observation of ATP-induced conformational changes in single P2X(4) receptors.

by Youichi Shinozaki, Koji Sumitomo, Makoto Tsuda, Schuichi Koizumi, Kazuhide Inoue, Keiichi Torimitsu
Published 2009-05-01

Astrocytic Ca2+ responses in the spinal dorsal horn by noxious stimuli to the skin

by Kohei Yoshihara, Tsuyoshi Matsuda, Yuta Kohro, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue, Makoto Tsuda
Published 2018-05-01

Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome

by Masaya Yasui, Yuki Menjyo, Kyohei Tokizane, Akiko Shiozawa, Makoto Tsuda, Kazuhide Inoue, Hiroshi Kiyama
Published 2019-03-01

Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain.

by Shigeo Hasegawa, Yuta Kohro, Miho Shiratori, Satoshi Ishii, Takao Shimizu, Makoto Tsuda, Kazuhide Inoue
Published 2010-01-01

Transcription factor IRF1 is responsible for IRF8-mediated IL-1β expression in reactive microglia

by Takahiro Masuda, Shosuke Iwamoto, Satsuki Mikuriya, Hidetoshi Tozaki-Saitoh, Tomohiko Tamura, Makoto Tsuda, Kazuhide Inoue
Published 2015-08-01

IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

by Takahiro Masuda, Makoto Tsuda, Ryohei Yoshinaga, Hidetoshi Tozaki-Saitoh, Keiko Ozato, Tomohiko Tamura, Kazuhide Inoue
Published 2012-04-01

New Inhibitory Effects of Cilnidipine on Microglial P2X7 Receptors and IL-1β Release: An Involvement in its Alleviating Effect on Neuropathic Pain

by Tomohiro Yamashita, Sawako Kamikaseda, Aya Tanaka, Hidetoshi Tozaki-Saitoh, Jose M. M. Caaveiro, Kazuhide Inoue, Makoto Tsuda
Published 2021-02-01

Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor

by Tomoko Nishimaki-Mogami, Mizuho Une, Tomofumi Fujino, Yoji Sato, Norimasa Tamehiro, Yosuke Kawahara, Koichi Shudo, Kazuhide Inoue
Published 2004-08-01

Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours

by Keisuke Koga, Kensho Kanehisa, Yuta Kohro, Miho Shiratori-Hayashi, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue, Hidemasa Furue, Makoto Tsuda
Published 2017-07-01

Duloxetine Inhibits Microglial P2X4 Receptor Function and Alleviates Neuropathic Pain after Peripheral Nerve Injury.

by Tomohiro Yamashita, Shota Yamamoto, Jiaming Zhang, Miho Kometani, Daisuke Tomiyama, Keita Kohno, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue, Makoto Tsuda
Published 2016-01-01

BK channels in microglia are required for morphine-induced hyperalgesia

by Yoshinori Hayashi, Saori Morinaga, Jing Zhang, Yasushi Satoh, Andrea L. Meredith, Takahiro Nakata, Zhou Wu, Shinichi Kohsaka, Kazuhide Inoue, Hiroshi Nakanishi
Published 2016-05-01

Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain

by Takahiro Masuda, Yui Ozono, Satsuki Mikuriya, Yuta Kohro, Hidetoshi Tozaki-Saitoh, Ken Iwatsuki, Hisayuki Uneyama, Reiko Ichikawa, Michael W. Salter, Makoto Tsuda, Kazuhide Inoue
Published 2016-08-01

Interferon Regulatory Factor 8 Expressed in Microglia Contributes to Tactile Allodynia Induced by Repeated Cold Stress in Rodents

by Takanori Akagi, Yuta Matsumura, Masaya Yasui, Emiko Minami, Hidemasa Inoue, Takahiro Masuda, Hidetoshi Tozaki-Saitoh, Tomohiko Tamura, Kazue Mizumura, Makoto Tsuda, Hiroshi Kiyama, Kazuhide Inoue
Published 2014-01-01

Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia

by Satoru Koyanagi, Naoki Kusunose, Marie Taniguchi, Takahiro Akamine, Yuki Kanado, Yui Ozono, Takahiro Masuda, Yuta Kohro, Naoya Matsunaga, Makoto Tsuda, Michael W. Salter, Kazuhide Inoue, Shigehiro Ohdo
Published 2016-10-01