Simultaneous Inhibition of PGE2 and PGI2 Signals Is Necessary to Suppress Hyperalgesia in Rat Inflammatory Pain Models

by Ryusuke Sugita, Harumi Kuwabara, Kazufumi Kubota, Kotaro Sugimoto, Toshihiro Kiho, Atsushi Tengeiji, Katsuhiro Kawakami, Kohei Shimada
Published 2016-01-01

A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models

by Ryusuke Sugita, Kazufumi Kubota, Kotaro Sugimoto, Yuki Tachida, Takahiro Shibayama, Toshihiro Kiho, Katsuhiro Kawakami, Kohei Shimada
Published 2016-02-01