Simvastatin and atorvastatin reduce the mechanical properties of tendon constructs in vitro and introduce catabolic changes in the gene expression pattern.

by Pernilla Eliasson, Rene B Svensson, Antonis Giannopoulos, Christian Eismark, Michael Kjær, Peter Schjerling, Katja M Heinemeier
Published 2017-01-01

Release of tensile strain on engineered human tendon tissue disturbs cell adhesions, changes matrix architecture, and induces an inflammatory phenotype.

by Monika L Bayer, Peter Schjerling, Andreas Herchenhan, Cedric Zeltz, Katja M Heinemeier, Lise Christensen, Michael Krogsgaard, Donald Gullberg, Michael Kjaer
Published 2014-01-01

Aging affects the transcriptional regulation of human skeletal muscle disuse atrophy.

by Charlotte Suetta, Ulrik Frandsen, Line Jensen, Mette Munk Jensen, Jakob G Jespersen, Lars G Hvid, Monika Bayer, Stine J Petersson, Henrik D Schrøder, Jesper L Andersen, Katja M Heinemeier, Per Aagaard, Peter Schjerling, Michael Kjaer
Published 2012-01-01