Oncogenic fusion protein FGFR2-PPHLN1: Requirements for biological activation, and efficacy of inhibitors

by Fangda Li, April N. Meyer, Malalage N. Peiris, Katelyn N. Nelson, Daniel J. Donoghue
Published 2020-12-01

Oncogenic mutations in IKKβ function through global changes induced by K63-linked ubiquitination and result in autocrine stimulation.

by April N Meyer, Leandro H Gallo, Juyeon Ko, Guillermo Cardenas, Katelyn N Nelson, Asma Siari, Alexandre R Campos, Thomas C Whisenant, Daniel J Donoghue
Published 2018-01-01