Genotype-property patient-phenotype relations suggest that proteome exhaustion can cause amyotrophic lateral sclerosis.

by Kasper P Kepp
Published 2015-01-01

A model of proteostatic energy cost and its use in analysis of proteome trends and sequence evolution.

by Kasper P Kepp, Pouria Dasmeh
Published 2014-01-01

Unfolding simulations of holomyoglobin from four mammals: identification of intermediates and β-sheet formation from partially unfolded states.

by Pouria Dasmeh, Kasper P Kepp
Published 2013-01-01

Stability mechanisms of a thermophilic laccase probed by molecular dynamics.

by Niels J Christensen, Kasper P Kepp
Published 2013-01-01

The dynamic mechanism of presenilin-1 function: Sensitive gate dynamics and loop unplugging control protein access

by Arun Kumar Somavarapu, Kasper P. Kepp
Published 2016-05-01

Characterization of an alkali- and halide-resistant laccase expressed in E. coli: CotA from Bacillus clausii.

by Søren Brander, Jørn D Mikkelsen, Kasper P Kepp
Published 2014-01-01

Molecular Recipe for γ‑Secretase Modulation from Computational Analysis of 60 Active Compounds

by Ning Tang, Arun K. Somavarapu, Kasper P. Kepp
Published 2018-12-01

A base measure of precision for protein stability predictors: structural sensitivity

by Octav Caldararu, Tom L. Blundell, Kasper P. Kepp
Published 2021-02-01

Positively selected sites in cetacean myoglobins contribute to protein stability.

by Pouria Dasmeh, Adrian W R Serohijos, Kasper P Kepp, Eugene I Shakhnovich
Published 2013-01-01

Rational design of a new Trypanosoma rangeli trans-sialidase for efficient sialylation of glycans.

by Carsten Jers, Malwina Michalak, Dorte M Larsen, Kasper P Kepp, Haiying Li, Yao Guo, Finn Kirpekar, Anne S Meyer, Jørn D Mikkelsen
Published 2014-01-01